PDB entry 2c6g

View 2c6g on RCSB PDB site
Description: membrane-bound glutamate carboxypeptidase II (gcpii) with bound glutamate
Class: hydrolase
Keywords: naaladase, neurodegenerative disease, peptidase, prostate cancer, psma, glycoprotein, hydrolase, alternative splicing, antigen, carboxypeptidase, dipeptidase, metal-binding, metalloprotease, multifunctional enzyme, polymorphism, signal-anchor, transmembrane, zinc
Deposited on 2005-11-09, released 2006-02-15
The last revision prior to the SCOP 1.73 freeze date was dated 2006-12-14, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.1867
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glutamate carboxypeptidase II
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2c6ga1, d2c6ga2, d2c6ga3
  • Heterogens: NAG, ZN, CA, CL, GLU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2c6gA (A:)
kssneatnitpkhnmkafldelkaenikkflynftqiphlagteqnfqlakqiqsqwkef
gldsvelahydvllsypnkthpnyisiinedgneifntslfeppppgyenvsdivppfsa
fspqgmpegdlvyvnyartedffklerdmkincsgkiviarygkvfrgnkvknaqlagak
gvilysdpadyfapgvksypdgwnlpgggvqrgnilnlngagdpltpgypaneyayrrgi
aeavglpsipvhpigyydaqkllekmggsappdsswrgslkvpynvgpgftgnfstqkvk
mhihstnevtriynvigtlrgavepdryvilgghrdswvfggidpqsgaavvheivrsfg
tlkkegwrprrtilfaswdaeefgllgstewaeensrllqergvayinadssiegnytlr
vdctplmyslvhnltkelkspdegfegkslyeswtkkspspefsgmprisklgsgndfev
ffqrlgiasgrarytknwetnkfsgyplyhsvyetyelvekfydpmfkyhltvaqvrggm
vfelansivlpfdcrdyavvlrkyadkiysismkhpqemktysvsfdslfsavknfteia
skfserlqdfdksnpivlrmmndqlmflerafidplglpdrpfyrhviyapsshnkyage
sfpgiydalfdieskvdpskawgevkrqiyvaaftvqaaaetlseva

    Sequence, based on observed residues (ATOM records): (download) 
    >2c6gA (A:)
nmkafldelkaenikkflynftqiphlagteqnfqlakqiqsqwkefgldsvelahydvl
lsypnkthpnyisiinedgneifntslfeppppgyenvsdivppfsafspqgmpegdlvy
vnyartedffklerdmkincsgkiviarygkvfrgnkvknaqlagakgvilysdpadyfa
pgvksypdgwnlpgggvqrgnilnlngagdpltpgypaneyayrrgiaeavglpsipvhp
igyydaqkllekmggsappdsswrgslkvpynvgpgfqkvkmhihstnevtriynvigtl
rgavepdryvilgghrdswvfggidpqsgaavvheivrsfgtlkkegwrprrtilfaswd
aeefgllgstewaeensrllqergvayinadssiegnytlrvdctplmyslvhnltkelk
spdegfegkslyeswtkkspspefsgmprisklgsgndfevffqrlgiasgrarytkngy
plyhsvyetyelvekfydpmfkyhltvaqvrggmvfelansivlpfdcrdyavvlrkyad
kiysismkhpqemktysvsfdslfsavknfteiaskfserlqdfdnpivlrmmndqlmfl
erafidplglpdrpfyrhviyapsshnkyagesfpgiydalfdieskvdpskawgevkrq
iyvaaftvqaaaetlseva