PDB entry 2c6f

View 2c6f on RCSB PDB site
Description: structure of human somatic angiontensin-I converting enzyme n domain
Class: hydrolase
Keywords: hydrolase, angiotensin-I converting enzyme, n domain, zinc metallopeptidase, metalloprotease, angiotensin, lisinopril, alternative splicing, carboxypeptidase, glycoprotein, metal-binding, phosphorylation, protease, transmembrane
Deposited on 2005-11-09, released 2006-11-08
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3.01 Å
R-factor: 0.224
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Angiotensin-converting enzyme, somatic isoform
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2c6fa_
  • Chain 'B':
    Compound: Angiotensin-converting enzyme, somatic isoform
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.04: d2c6fb_
  • Heterogens: NAG, ZN, CL, ACT, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2c6fA (A:)
ldpglqpgnfsadeagaqlfaqsynssaeqvlfqsvaaswahdtnitaenarrqeeaall
sqefaeawgqkakelyepiwqnftdpqlrriigavrtlgsanlplakrqqynallsnmsr
iystakvclpnktatcwsldpdltnilassrsyamllfawegwhnaagiplkplyedfta
lsneaykqdgftdtgaywrswynsptfeddlehlyqqleplylnlhafvrralhrrygdr
yinlrgpipahllgdmwaqsweniydmvvpfpdkpnldvtstmlqqgwnathmfrvaeef
ftslelspmppefwegsmlekpadgrevvchasawdfynrkdfrikqctrvtmdqlstvh
hemghiqyylqykdlpvslrrganpgfheaigdvlalsvstpehlhkiglldrvtndtes
dinyllkmalekiaflpfgylvdqwrwgvfsgrtppsrynfdwwylrtkyqgicppvtrn
ethfdagakfhvpnvtpyiryfvsfvlqfqfhealckeagyegplhqcdiyrstkagakl
rkvlqagssrpwqevlkdmvgldaldaqpllkyfqpvtqwlqeqnqqngevlgwpeyqwh
pplpdnypegid

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2c6fB (B:)
ldpglqpgnfsadeagaqlfaqsynssaeqvlfqsvaaswahdtnitaenarrqeeaall
sqefaeawgqkakelyepiwqnftdpqlrriigavrtlgsanlplakrqqynallsnmsr
iystakvclpnktatcwsldpdltnilassrsyamllfawegwhnaagiplkplyedfta
lsneaykqdgftdtgaywrswynsptfeddlehlyqqleplylnlhafvrralhrrygdr
yinlrgpipahllgdmwaqsweniydmvvpfpdkpnldvtstmlqqgwnathmfrvaeef
ftslelspmppefwegsmlekpadgrevvchasawdfynrkdfrikqctrvtmdqlstvh
hemghiqyylqykdlpvslrrganpgfheaigdvlalsvstpehlhkiglldrvtndtes
dinyllkmalekiaflpfgylvdqwrwgvfsgrtppsrynfdwwylrtkyqgicppvtrn
ethfdagakfhvpnvtpyiryfvsfvlqfqfhealckeagyegplhqcdiyrstkagakl
rkvlqagssrpwqevlkdmvgldaldaqpllkyfqpvtqwlqeqnqqngevlgwpeyqwh
pplpdnypegid

    Sequence, based on observed residues (ATOM records): (download) 
    >2c6fB (B:)
dpglqpgnfsadeagaqlfaqsynssaeqvlfqsvaaswahdtnitaenarrqeeaalls
qefaeawgqkakelyepiwqnftdpqlrriigavrtlgsanlplakrqqynallsnmsri
ystakvclpnktatcwsldpdltnilassrsyamllfawegwhnaagiplkplyedftal
sneaykqdgftdtgaywrswynsptfeddlehlyqqleplylnlhafvrralhrrygdry
inlrgpipahllgdmwaqsweniydmvvpfpdkpnldvtstmlqqgwnathmfrvaeeff
tslelspmppefwegsmlekpadgrevvchasawdfynrkdfrikqctrvtmdqlstvhh
emghiqyylqykdlpvslrrganpgfheaigdvlalsvstpehlhkiglldrvtndtesd
inyllkmalekiaflpfgylvdqwrwgvfsgrtppsrynfdwwylrtkyqgicppvtrne
thfdagakfhvpnvtpyiryfvsfvlqfqfhealckeagyegplhqcdiyrstkagaklr
kvlqagssrpwqevlkdmvgldaldaqpllkyfqpvtqwlqeqnqqngevlgwpeyqwhp
plpdnypegid