PDB entry 2c4o

View 2c4o on RCSB PDB site
Description: crystal structure of human ubiquitin-conjugating enzyme ubch5b
Class: ligase
Keywords: thioesterification, ubiquitin-conjugating enzyme, ligase, ubl conjugation pathway
Deposited on 2005-10-21, released 2006-11-22
The last revision prior to the SCOP 1.75 freeze date was dated 2006-11-22, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.94 Å
R-factor: 0.227
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ubiquitin-conjugating enzyme e2 d2
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2c4oa1
  • Chain 'B':
    Compound: ubiquitin-conjugating enzyme e2 d2
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2c4ob1
  • Chain 'C':
    Compound: ubiquitin-conjugating enzyme e2 d2
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2c4oc1
  • Chain 'D':
    Compound: ubiquitin-conjugating enzyme e2 d2
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2c4od1
  • Heterogens: SO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2c4oA (A:)
mkhhhhhhpmsglvprgsmalkrihkelndlardppaqcsagpvgddmfhwqatimgpnd
spyqggvffltihfptdypfkppkvafttriyhpninsngsicldilrsqwspaltiskv
llsicsllcdpnpddplvpeiariyktdrekynriarewtqkyam

    Sequence, based on observed residues (ATOM records): (download) 
    >2c4oA (A:)
rgsmalkrihkelndlardppaqcsagpvgddmfhwqatimgpndspyqggvffltihfp
tdypfkppkvafttriyhpninsngsicldilrsqwspaltiskvllsicsllcdpnpdd
plvpeiariyktdrekynriarewtqkyam

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2c4oB (B:)
mkhhhhhhpmsglvprgsmalkrihkelndlardppaqcsagpvgddmfhwqatimgpnd
spyqggvffltihfptdypfkppkvafttriyhpninsngsicldilrsqwspaltiskv
llsicsllcdpnpddplvpeiariyktdrekynriarewtqkyam

    Sequence, based on observed residues (ATOM records): (download) 
    >2c4oB (B:)
rgsmalkrihkelndlardppaqcsagpvgddmfhwqatimgpndspyqggvffltihfp
tdypfkppkvafttriyhpninsngsicldilrsqwspaltiskvllsicsllcdpnpdd
plvpeiariyktdrekynriarewtqkyam

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2c4oC (C:)
mkhhhhhhpmsglvprgsmalkrihkelndlardppaqcsagpvgddmfhwqatimgpnd
spyqggvffltihfptdypfkppkvafttriyhpninsngsicldilrsqwspaltiskv
llsicsllcdpnpddplvpeiariyktdrekynriarewtqkyam

    Sequence, based on observed residues (ATOM records): (download) 
    >2c4oC (C:)
rgsmalkrihkelndlardppaqcsagpvgddmfhwqatimgpndspyqggvffltihfp
tdypfkppkvafttriyhpninsngsicldilrsqwspaltiskvllsicsllcdpnpdd
plvpeiariyktdrekynriarewtqkyam

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2c4oD (D:)
mkhhhhhhpmsglvprgsmalkrihkelndlardppaqcsagpvgddmfhwqatimgpnd
spyqggvffltihfptdypfkppkvafttriyhpninsngsicldilrsqwspaltiskv
llsicsllcdpnpddplvpeiariyktdrekynriarewtqkyam

    Sequence, based on observed residues (ATOM records): (download) 
    >2c4oD (D:)
rgsmalkrihkelndlardppaqcsagpvgddmfhwqatimgpndspyqggvffltihfp
tdypfkppkvafttriyhpninsngsicldilrsqwspaltiskvllsicsllcdpnpdd
plvpeiariyktdrekynriarewtqkyam