PDB entry 2c46

View 2c46 on RCSB PDB site
Description: CRYSTAL STRUCTURE OF THE HUMAN RNA guanylyltransferase and 5'- phosphatase
Class: transferase
Keywords: phosphatase, transferase, hydrolase, mRNA processing, multifunctional enzyme, nucleotidyltransferase
Deposited on 2005-10-15, released 2005-11-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-24, with a file datestamp of 2018-01-19.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: mRNA capping enzyme
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60942 (22-End)
      • expression tag (16-21)
    Domains in SCOPe 2.08: d2c46a1, d2c46a2
  • Chain 'B':
    Compound: mRNA capping enzyme
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60942
      • expression tag (15-21)
    Domains in SCOPe 2.08: d2c46b1, d2c46b2
  • Chain 'C':
    Compound: mRNA capping enzyme
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60942
      • expression tag (15-21)
    Domains in SCOPe 2.08: d2c46c1, d2c46c2
  • Chain 'D':
    Compound: mRNA capping enzyme
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2c46d_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2c46A (A:)
mhhhhhhssgvdlgtenlyfqsmahnkipprwlncprrgqpvagrflplktmlgprydsq
vaeenrfhpsmlsnylkslkvkmgllvdltntsrfydrndiekegikyiklqckghgecp
ttentetfirlcerfnernppeligvhcthgfnrtgflicaflvekmdwsieaavatfaq
arppgiykgdylkelfrrygdieeappppllpdwcfeddededededgkkesetgssasf
g

    Sequence, based on observed residues (ATOM records): (download) 
    >2c46A (A:)
nlyfqsmahnkipprwlncprrgqpvagrflplktmlgprydsqvaeenrfhpsmlsnyl
kslkvkmgllvdltntsrfydrndiekegikyiklqckghgecpttentetfirlcerfp
eligvhcthgfnrtgflicaflvekmdwsieaavatfaqarppgiykgdylkelfrrygd
ieeappppllpdwcfedded

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2c46B (B:)
mhhhhhhssgvdlgtenlyfqsmahnkipprwlncprrgqpvagrflplktmlgprydsq
vaeenrfhpsmlsnylkslkvkmgllvdltntsrfydrndiekegikyiklqckghgecp
ttentetfirlcerfnernppeligvhcthgfnrtgflicaflvekmdwsieaavatfaq
arppgiykgdylkelfrrygdieeappppllpdwcfeddededededgkkesetgssasf
g

    Sequence, based on observed residues (ATOM records): (download) 
    >2c46B (B:)
enlyfqsnkipprwlncprrgqpvagrflplktmlgprydsqvaeenrfhpsmlsnylks
lkvkmgllvdltntsrfydrndiekegikyiklqckghgecpttentetfirlcerfner
neligvhcthgfnrtgflicaflvekmdwsieaavatfaqarppgiykgdylkelfrryg
dieeappppllpdwcfedded

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2c46C (C:)
mhhhhhhssgvdlgtenlyfqsmahnkipprwlncprrgqpvagrflplktmlgprydsq
vaeenrfhpsmlsnylkslkvkmgllvdltntsrfydrndiekegikyiklqckghgecp
ttentetfirlcerfnernppeligvhcthgfnrtgflicaflvekmdwsieaavatfaq
arppgiykgdylkelfrrygdieeappppllpdwcfeddededededgkkesetgssasf
g

    Sequence, based on observed residues (ATOM records): (download) 
    >2c46C (C:)
enlyfqsnkipprwlncprrgqpvagrflplktmlgprydsqvaeenrfhpsmlsnylks
lkvkmgllvdltntsrfydrndiekegikyiklqckghgecpttentetfirlcerfeli
gvhcthgfnrtgflicaflvekmdwsieaavatfaqarppgiykgdylkelfrrygdiee
appppllpdwcfedded

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2c46D (D:)
mhhhhhhssgvdlgtenlyfqsmahnkipprwlncprrgqpvagrflplktmlgprydsq
vaeenrfhpsmlsnylkslkvkmgllvdltntsrfydrndiekegikyiklqckghgecp
ttentetfirlcerfnernppeligvhcthgfnrtgflicaflvekmdwsieaavatfaq
arppgiykgdylkelfrrygdieeappppllpdwcfeddededededgkkesetgssasf
g

    Sequence, based on observed residues (ATOM records): (download) 
    >2c46D (D:)
nkipprwlncprrgqpvagrflplktmlgprydsqvaeenrfhpsmlsnylksvkmgllv
dltntsrfydrndiekegikyiklqckghgecpttentetfirlcerfeligvhcthgfn
rtgflicaflvekmdwsieaavatfaqarppgiykgdylkelfrrygdieeappppllpd
wcfeddede