PDB entry 2byw

View 2byw on RCSB PDB site
Description: Structure of escherichia coli beta-ketoacyl (acyl carrier protein) synthase I LYS328ALA mutant
Class: transferase
Keywords: transferase, condensing enzyme, fatty acid biosynthesis, kas I, acyltransferase, lipid synthesis
Deposited on 2005-08-09, released 2005-09-09
The last revision prior to the SCOPe 2.05 freeze date was dated 2014-02-19, with a file datestamp of 2014-02-14.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.181
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-oxoacyl-[acyl-carrier-protein] synthase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BYW
      • engineered mutation (15)
      • engineered mutation (339)
    • Uniprot P14926 (12-417)
    Domains in SCOPe 2.05: d2bywa1, d2bywa2
  • Chain 'B':
    Compound: 3-oxoacyl-[acyl-carrier-protein] synthase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BYW
      • engineered mutation (15)
      • engineered mutation (339)
    • Uniprot P14926 (12-417)
    Domains in SCOPe 2.05: d2bywb1, d2bywb2
  • Chain 'C':
    Compound: 3-oxoacyl-[acyl-carrier-protein] synthase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BYW
      • engineered mutation (15)
      • engineered mutation (339)
    • Uniprot P14926 (12-417)
    Domains in SCOPe 2.05: d2bywc1, d2bywc2
  • Chain 'D':
    Compound: 3-oxoacyl-[acyl-carrier-protein] synthase I
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BYW
      • engineered mutation (15)
      • engineered mutation (339)
    • Uniprot P14926 (12-417)
    Domains in SCOPe 2.05: d2bywd1, d2bywd2
  • Heterogens: NH4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2bywA (A:)
mrgshhhhhhgsmkrvvitglgivssignnqqevlaslregrsgitfsqelkdsgmrshv
wgnvkldttglidrkvvrfmsdasiyaflsmeqaiadaglspeayqnnprvgliagsggg
sprfqvfgadamrgprglkavgpyvvtkamasgvsaclatpfkihgvnysissacatsah
cignaveqiqlgkqdivfagggeelcwemacefdamgalstkyndtpekasrtydahrdg
fviaggggmvvveelehalargahiyaeivgygatsdgadmvapsgegavrcmkmamhgv
dtpidylnshgtstpvgdvkelaairevfgdkspaisataamtghslgaagvqeaiysll
mlehgfiapsinieeldeqaaglnivtettdrelttvmsnsfgfggtnatlvmrklkd

    Sequence, based on observed residues (ATOM records): (download) 
    >2bywA (A:)
mkrvvitglgivssignnqqevlaslregrsgitfsqelkdsgmrshvwgnvkldttgli
drkvvrfmsdasiyaflsmeqaiadaglspeayqnnprvgliagsgggsprfqvfgadam
rgprglkavgpyvvtkamasgvsaclatpfkihgvnysissacatsahcignaveqiqlg
kqdivfagggeelcwemacefdamgalstkyndtpekasrtydahrdgfviaggggmvvv
eelehalargahiyaeivgygatsdgadmvapsgegavrcmkmamhgvdtpidylnshgt
stpvgdvkelaairevfgdkspaisataamtghslgaagvqeaiysllmlehgfiapsin
ieeldeqaaglnivtettdrelttvmsnsfgfggtnatlvmrklkd

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >2bywB (B:)
mrgshhhhhhgsmkrvvitglgivssignnqqevlaslregrsgitfsqelkdsgmrshv
wgnvkldttglidrkvvrfmsdasiyaflsmeqaiadaglspeayqnnprvgliagsggg
sprfqvfgadamrgprglkavgpyvvtkamasgvsaclatpfkihgvnysissacatsah
cignaveqiqlgkqdivfagggeelcwemacefdamgalstkyndtpekasrtydahrdg
fviaggggmvvveelehalargahiyaeivgygatsdgadmvapsgegavrcmkmamhgv
dtpidylnshgtstpvgdvkelaairevfgdkspaisataamtghslgaagvqeaiysll
mlehgfiapsinieeldeqaaglnivtettdrelttvmsnsfgfggtnatlvmrklkd

    Sequence, based on observed residues (ATOM records): (download) 
    >2bywB (B:)
mkrvvitglgivssignnqqevlaslregrsgitfsqelkdsgmrshvwgnvkldttgli
drkvvrfmsdasiyaflsmeqaiadaglspeayqnnprvgliagsgggsprfqvfgadam
rgprglkavgpyvvtkamasgvsaclatpfkihgvnysissacatsahcignaveqiqlg
kqdivfagggeelcwemacefdamgalstkyndtpekasrtydahrdgfviaggggmvvv
eelehalargahiyaeivgygatsdgadmvapsgegavrcmkmamhgvdtpidylnshgt
stpvgdvkelaairevfgdkspaisataamtghslgaagvqeaiysllmlehgfiapsin
ieeldeqaaglnivtettdrelttvmsnsfgfggtnatlvmrklkd

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >2bywC (C:)
mrgshhhhhhgsmkrvvitglgivssignnqqevlaslregrsgitfsqelkdsgmrshv
wgnvkldttglidrkvvrfmsdasiyaflsmeqaiadaglspeayqnnprvgliagsggg
sprfqvfgadamrgprglkavgpyvvtkamasgvsaclatpfkihgvnysissacatsah
cignaveqiqlgkqdivfagggeelcwemacefdamgalstkyndtpekasrtydahrdg
fviaggggmvvveelehalargahiyaeivgygatsdgadmvapsgegavrcmkmamhgv
dtpidylnshgtstpvgdvkelaairevfgdkspaisataamtghslgaagvqeaiysll
mlehgfiapsinieeldeqaaglnivtettdrelttvmsnsfgfggtnatlvmrklkd

    Sequence, based on observed residues (ATOM records): (download) 
    >2bywC (C:)
mkrvvitglgivssignnqqevlaslregrsgitfsqelkdsgmrshvwgnvkldttgli
drkvvrfmsdasiyaflsmeqaiadaglspeayqnnprvgliagsgggsprfqvfgadam
rgprglkavgpyvvtkamasgvsaclatpfkihgvnysissacatsahcignaveqiqlg
kqdivfagggeelcwemacefdamgalstkyndtpekasrtydahrdgfviaggggmvvv
eelehalargahiyaeivgygatsdgadmvapsgegavrcmkmamhgvdtpidylnshgt
stpvgdvkelaairevfgdkspaisataamtghslgaagvqeaiysllmlehgfiapsin
ieeldeqaaglnivtettdrelttvmsnsfgfggtnatlvmrklkd

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >2bywD (D:)
mrgshhhhhhgsmkrvvitglgivssignnqqevlaslregrsgitfsqelkdsgmrshv
wgnvkldttglidrkvvrfmsdasiyaflsmeqaiadaglspeayqnnprvgliagsggg
sprfqvfgadamrgprglkavgpyvvtkamasgvsaclatpfkihgvnysissacatsah
cignaveqiqlgkqdivfagggeelcwemacefdamgalstkyndtpekasrtydahrdg
fviaggggmvvveelehalargahiyaeivgygatsdgadmvapsgegavrcmkmamhgv
dtpidylnshgtstpvgdvkelaairevfgdkspaisataamtghslgaagvqeaiysll
mlehgfiapsinieeldeqaaglnivtettdrelttvmsnsfgfggtnatlvmrklkd

    Sequence, based on observed residues (ATOM records): (download) 
    >2bywD (D:)
mkrvvitglgivssignnqqevlaslregrsgitfsqelkdsgmrshvwgnvkldttgli
drkvvrfmsdasiyaflsmeqaiadaglspeayqnnprvgliagsgggsprfqvfgadam
rgprglkavgpyvvtkamasgvsaclatpfkihgvnysissacatsahcignaveqiqlg
kqdivfagggeelcwemacefdamgalstkyndtpekasrtydahrdgfviaggggmvvv
eelehalargahiyaeivgygatsdgadmvapsgegavrcmkmamhgvdtpidylnshgt
stpvgdvkelaairevfgdkspaisataamtghslgaagvqeaiysllmlehgfiapsin
ieeldeqaaglnivtettdrelttvmsnsfgfggtnatlvmrklkd