PDB entry 2boh
View 2boh on RCSB PDB site
Description: crystal structure of factor xa in complex with compound "1"
Class: complex (hydrolase/inhibitor)
Keywords: protein-inhibitor complex, blood coagulation factor, serine proteinase, rational drug design, calcium-binding, egf-like domain, gamma-carboxyglutamic acid, glycoprotein, hydrolase, hydroxylation, plasma, polymorphism, protease, repeat, serine protease, vitamin k, zymogen, hydrolase-inhibitor complex
Deposited on
2005-04-11, released
2006-04-05
The last revision prior to the SCOP 1.75 freeze date was dated
2006-04-05, with a file datestamp of
2007-06-28.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.207
AEROSPACI score: 0.48
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: coagulation factor xa
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d2boha1 - Chain 'B':
Compound: coagulation factor xa
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d2bohb1 - Heterogens: CA, IIA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2bohA (A:)
eemkkghlerecmeetcsyeearevfedsdktnefwnkykdgdqcetspcqnqgkckdgl
geytctclegfegkncelftrklcsldngdcdqfcheeqnsvvcscargytladngkaci
ptgpypcgkqtler
Sequence, based on observed residues (ATOM records): (download)
>2bohA (A:)
rklcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtler
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2bohB (B:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktrglpka
kshapevitssplk
Sequence, based on observed residues (ATOM records): (download)
>2bohB (B:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktr