PDB entry 2bnr

View 2bnr on RCSB PDB site
Description: Structural and kinetic basis for heightened immunogenicity of T cell vaccines
Class: immune system/receptor
Keywords: IMMUNE SYSTEM/RECEPTOR, IMMUNE SYSTEM-RECEPTOR-COMPLEX, TCR, MHC, IMMUNODOMINANCE, FLU, COMPLEX, TRANSMEMBRANE, GLYCOPROTEIN, T-CELL, RECEPTOR, SUPERAGONIST PEPTIDE T-CELL VACCINES, IMMUNE SYSTEM-RECEPTOR complex
Deposited on 2005-03-31, released 2005-05-23
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-11-25, with a file datestamp of 2015-11-20.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla class I histocompatibility antigen
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2bnra1, d2bnra2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BNR (0-0)
    • Uniprot P61769 (1-99)
    Domains in SCOPe 2.06: d2bnrb2, d2bnrb3
  • Chain 'C':
    Compound: synthetic peptide
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BNR (0-8)
  • Chain 'D':
    Compound: T-cell receptor alpha chain v region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BNR (0-202)
    Domains in SCOPe 2.06: d2bnrd1, d2bnrd2
  • Chain 'E':
    Compound: T-cell receptor beta chain c region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 2BNR (0-110)
      • conflict (114-115)
      • conflict (147)
      • conflict (167)
      • conflict (185)
      • conflict (199)
    • Uniprot P01850 (111-240)
    Domains in SCOPe 2.06: d2bnre1, d2bnre2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2bnrA (A:)
gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
dgetrkvkahsqthrvdlgtlrgyynqseagshtvqrmygcdvgsdwrflrgyhqyaydg
kdyialkedlrswtaadmaaqttkhkweaahvaeqlraylegtcvewlrrylengketlq
rtdapkthmthhavsdheatlrcwalsfypaeitltwqrdgedqtqdtelvetrpagdgt
fqkwaavvvpsgqeqrytchvqheglpkpltlrwep

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2bnrB (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2bnrD (D:)
qevtqipaalsvpegenlvlncsftdsaiynlqwfrqdpgkgltsllliqssqreqtsgr
lnasldkssgrstlyiaasqpgdsatylcavrptsggsyiptfgrgtslivhpyiqnpdp
avyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdkcvldmrsmdfksnsavawsn
ksdfacanafnnsiipedtffps

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2bnrE (E:)
gvtqtpkfqvlktgqsmtlqcaqdmnheymswyrqdpgmglrlihysvgagitdqgevpn
gynvsrsttedfplrllsaapsqtsvyfcassyvgntgelffgegsrltvledlknvfpp
evavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvctdpqplkeqpal
ndsryalssrlrvsatfwqdprnhfrcqvqfyglsendewtqdrakpvtqivsaeawgra
d