PDB entry 2bhh

View 2bhh on RCSB PDB site
Description: human cyclin dependent protein kinase 2 in complex with the inhibitor 4-hydroxypiperindinesulfonyl-indirubine
Class: transferase
Keywords: 3d-structure, arylamine n-acetyltransferase, ATP-binding, cell cycle, cell division, drug metabolism, isoniazid, mitosis, mycobacteria, nat, phosphorylation, polymorphism, serine-threonine-protein kinase, transferase
Deposited on 2005-01-11, released 2005-03-09
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.244
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2bhha_
  • Heterogens: RYU, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2bhhA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >2bhhA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkipstaireisllkelnhpnivklldv
    ihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdlk
    pqnllintegaikladfglvtlwyrapeillgckyystavdiwslgcifaemvtrralfp
    gdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppldedgrslls
    qmlhydpnkrisakaalahpffqdvtkpvphlrl