PDB entry 2be6

View 2be6 on RCSB PDB site
Description: 2.0 A crystal structure of the CaV1.2 IQ domain-Ca/CaM complex
Class: membrane protein
Keywords: calmodulin, calcium channel, IQ domain, inactivation, facilitation, calcium-dependent, gating, voltage-gated, MEMBRANE PROTEIN
Deposited on 2005-10-23, released 2005-11-15
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-18, with a file datestamp of 2017-10-13.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Calmodulin 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CALM2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2be6a_
  • Chain 'B':
    Compound: Calmodulin 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CALM2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2be6b_
  • Chain 'C':
    Compound: Calmodulin 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CALM2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2be6c_
  • Chain 'D':
    Compound: Voltage-dependent L-type calcium channel alpha-1C subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Voltage-dependent L-type calcium channel alpha-1C subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Voltage-dependent L-type calcium channel alpha-1C subunit
    Species: Homo sapiens [TaxId:9606]
    Gene: CACNA1C, CACH2, CACN2, CACNL1A1, CCHL1A1
    Database cross-references and differences (RAF-indexed):
  • Heterogens: CA, NI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2be6A (A:)
    madqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadg
    ngtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltde
    evdemireadidgdgqvnyeefvqmmtakl
    

    Sequence, based on observed residues (ATOM records): (download)
    >2be6A (A:)
    qlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngt
    idfpefltmmarkmkseeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevdemi
    readidgdgqvnyeefvqmmt
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >2be6B (B:)
    madqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadg
    ngtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltde
    evdemireadidgdgqvnyeefvqmmtakl
    

    Sequence, based on observed residues (ATOM records): (download)
    >2be6B (B:)
    lteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngti
    dfpefltmmarkmkdeeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevdemir
    eadidgdgqvnyeefvqmmt
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >2be6C (C:)
    madqlteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadg
    ngtidfpefltmmarkmkdtdseeeireafrvfdkdgngyisaaelrhvmtnlgekltde
    evdemireadidgdgqvnyeefvqmmtakl
    

    Sequence, based on observed residues (ATOM records): (download)
    >2be6C (C:)
    lteeqiaefkeafslfdkdgdgtittkelgtvmrslgqnpteaelqdminevdadgngti
    dfpefltmmarkeeeireafrvfdkdgngyisaaelrhvmtnlgekltdeevdemiread
    idgdgqvnyeefvqmmt
    

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.