PDB entry 2bcu

View 2bcu on RCSB PDB site
Description: DNA polymerase lambda in complex with a DNA duplex containing an unpaired Damp and a T:T mismatch
Class: Transferase, Lyase/DNA
Keywords: misalignment, extrahelical, mutagenesis, mutation, deletion, streisinger, slippage, Transferase, Lyase/DNA COMPLEX
Deposited on 2005-10-19, released 2006-03-07
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.219
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase lambda
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2bcua1, d2bcua2, d2bcua3
  • Chain 'D':
    Compound: 5'-d(p*gp*cp*cp*g)-3'
  • Chain 'P':
    Compound: 5'-d(*cp*ap*gp*tp*tp*cp*g)-3'
  • Chain 'T':
    Compound: 5'-d(*cp*gp*gp*cp*cp*gp*ap*tp*ap*cp*tp*g)-3'
  • Heterogens: NA, PPV, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2bcuA (A:)
maqpssqkatnhnlhiteklevlakaysvqgdkwralgyakainalksfhkpvtsyqeac
sipgigkrmaekiieilesghlrkldhisesvpvlelfsniwgagtktaqmwyqqgfrsl
edirsqaslttqqaiglkhysdflermpreeateieqtvqkaaqafnsgllcvacgsyrr
gkatcgdvdvlithpdgrshrgifsrlldslrqegfltddlvsqeengqqqkylgvcrlp
gpgrrhrrldiivvpysefacallyftgsahfnrsmralaktkgmslsehalstavvrnt
hgckvgpgrvlptptekdvfrllglpyrepaerdw

    Sequence, based on observed residues (ATOM records): (download) 
    >2bcuA (A:)
tnhnlhiteklevlakaysvqgdkwralgyakainalksfhkpvtsyqeacsipgigkrm
aekiieilesghlrkldhisesvpvlelfsniwgagtktaqmwyqqgfrsledirsqasl
ttqqaiglkhysdflermpreeateieqtvqkaaqafnsgllcvacgsyrrgkatcgdvd
vlithpdgrshrgifsrlldslrqegfltddlvsqeengqqqkylgvcrlpgpgrrhrrl
diivvpysefacallyftgsahfnrsmralaktkgmslsehalstavvrnthgckvgpgr
vlptptekdvfrllglpyrepaerdw

  • Chain 'D':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.