PDB entry 2bck

View 2bck on RCSB PDB site
Description: Crystal Structure of HLA-A*2402 Complexed with a telomerase peptide
Class: immune system
Keywords: Immunoglobulin Domains, Beta barrels, MHC Fold
Deposited on 2005-10-19, released 2006-01-10
The last revision prior to the SCOP 1.73 freeze date was dated 2006-01-10, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.187
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: HLA class I histocompatibility antigen, A-24 alpha chain
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05534 (0-275)
      • cloning artifact (276-285)
    Domains in SCOP 1.73: d2bcka1, d2bcka2
  • Chain 'B':
    Compound: Beta-2-microglobulin
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • initiating methionine (0)
    Domains in SCOP 1.73: d2bckb1
  • Chain 'C':
    Compound: Telomerase reverse transcriptase
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: HLA class I histocompatibility antigen, A-24 alpha chain
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05534 (0-275)
      • cloning artifact (276-285)
    Domains in SCOP 1.73: d2bckd1, d2bckd2
  • Chain 'E':
    Compound: Beta-2-microglobulin
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61769 (1-99)
      • initiating methionine (0)
    Domains in SCOP 1.73: d2bcke1
  • Chain 'F':
    Compound: Telomerase reverse transcriptase
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Heterogens: SO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2bckA (A:)
    gshsmryfstsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
    deetgkvkahsqtdrenlrialryynqseagshtlqmmfgcdvgsdgrflrgyhqyaydg
    kdyialkedlrswtaadmaaqitkrkweaahvaeqqraylegtcvdglrrylengketlq
    rtdppkthmthhpisdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdgt
    fqkwaavvvpsgeeqrytchvqheglpkpltlrwepgsggglndifeaqkiewh
    

    Sequence, based on observed residues (ATOM records): (download)
    >2bckA (A:)
    gshsmryfstsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
    deetgkvkahsqtdrenlrialryynqseagshtlqmmfgcdvgsdgrflrgyhqyaydg
    kdyialkedlrswtaadmaaqitkrkweaahvaeqqraylegtcvdglrrylengketlq
    rtdppkthmthhpisdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdgt
    fqkwaavvvpsgeeqrytchvqheglpkpltlrwepgsggglndif
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2bckB (B:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >2bckD (D:)
    gshsmryfstsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
    deetgkvkahsqtdrenlrialryynqseagshtlqmmfgcdvgsdgrflrgyhqyaydg
    kdyialkedlrswtaadmaaqitkrkweaahvaeqqraylegtcvdglrrylengketlq
    rtdppkthmthhpisdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdgt
    fqkwaavvvpsgeeqrytchvqheglpkpltlrwepgsggglndifeaqkiewh
    

    Sequence, based on observed residues (ATOM records): (download)
    >2bckD (D:)
    gshsmryfstsvsrpgrgeprfiavgyvddtqfvrfdsdaasqrmeprapwieqegpeyw
    deetgkvkahsqtdrenlrialryynqseagshtlqmmfgcdvgsdgrflrgyhqyaydg
    kdyialkedlrswtaadmaaqitkrkweaahvaeqqraylegtcvdglrrylengketlq
    rtdppkthmthhpisdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdgt
    fqkwaavvvpsgeeqrytchvqheglpkpltlrwepgsggglndif
    

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2bckE (E:)
    miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
    wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
    

  • Chain 'F':
    No sequence available.