PDB entry 2bc9

View 2bc9 on RCSB PDB site
Description: Crystal-structure of the N-terminal large GTPase Domain of human Guanylate Binding protein 1 (hGBP1) in complex with non-hydrolysable GTP analogue GppNHp
Class: signaling protein
Keywords: Protein- guanine nucleotide complex, SIGNALING PROTEIN
Deposited on 2005-10-19, released 2006-03-07
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.234
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: interferon-induced guanylate-binding protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: GBP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2bc9a1, d2bc9a2
  • Heterogens: MG, GNP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2bc9A (A:)
    mhhhhhhmrgsmaseihmtgpmclientngrlmanpealkilsaitqpmvvvaivglyrt
    gksylmnklagkkkgfslgstvqshtkgiwmwcvphpkkpghilvlldteglgdvekgdn
    qndswifalavllsstfvynsigtinqqamdqlyyvtelthrirsksspdenenevedsa
    dfvsffpdfvwtlrdfsldleadgqpltpdeyltyslklkkgtsqkdetfnlprlcirkf
    fpkkkcfvfdrpvhrrklaqleklqdeeldpefvqqvadfcsyifsnsktktlsggiqvn
    gprleslvltyvnaissgdlpcmenavl
    

    Sequence, based on observed residues (ATOM records): (download)
    >2bc9A (A:)
    aseihmtgpmclientngrlmanpealkilsaitqpmvvvaivglyrtgksylmnklagk
    kkgfslgstvqshtkgiwmwcvphpkkpghilvlldteglgdvekgdnqndswifalavl
    lsstfvynsigtinqqamdqlyyvtelthrirsksdfvsffpdfvwtlrdfsldleadgq
    pltpdeyltyslklkkgtsqkdetfnlprlcirkffpkkkcfvfdrpvhrrklaqleklq
    deeldpefvqqvadfcsyifsnsktktlsggiqvngprleslvltyvnaissgd