PDB entry 2b76

View 2b76 on RCSB PDB site
Description: E. coli Quinol fumarate reductase FrdA E49Q mutation
Class: oxidoreductase
Keywords: fumarate reductase, succinate dehydrogenase, electron transfer, respiration, krebs cycle, membrane protein, OXIDOREDUCTASE
Deposited on 2005-10-03, released 2006-02-21
The last revision prior to the SCOPe 2.03 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 3.3 Å
R-factor: 0.248
AEROSPACI score: 0.1 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Fumarate reductase flavoprotein subunit
    Species: Escherichia coli [TaxId:562]
    Gene: FrdA
    Database cross-references and differences (RAF-indexed):
    • GB FRDA_ECOLI (0-End)
      • engineered (49)
    Domains in SCOPe 2.03: d2b76a1, d2b76a2, d2b76a3
  • Chain 'B':
    Compound: fumarate reductase iron-sulfur protein
    Species: Escherichia coli [TaxId:562]
    Gene: frdB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2b76b1, d2b76b2
  • Chain 'C':
    Compound: Fumarate reductase subunit C
    Species: Escherichia coli [TaxId:562]
    Gene: frdC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2b76c1
  • Chain 'D':
    Compound: Fumarate reductase subunit D
    Species: Escherichia coli [TaxId:562]
    Gene: frdD
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2b76d1
  • Chain 'M':
    Compound: Fumarate reductase flavoprotein subunit
    Species: Escherichia coli [TaxId:562]
    Gene: FrdA
    Database cross-references and differences (RAF-indexed):
    • GB FRDA_ECOLI (0-End)
      • engineered (49)
    Domains in SCOPe 2.03: d2b76m1, d2b76m2, d2b76m3
  • Chain 'N':
    Compound: fumarate reductase iron-sulfur protein
    Species: Escherichia coli [TaxId:562]
    Gene: frdB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2b76n1, d2b76n2
  • Chain 'O':
    Compound: Fumarate reductase subunit C
    Species: Escherichia coli [TaxId:562]
    Gene: frdC
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2b76o1
  • Chain 'P':
    Compound: Fumarate reductase subunit D
    Species: Escherichia coli [TaxId:562]
    Gene: frdD
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d2b76p1
  • Heterogens: FLC, FES, F3S, SF4, FAD, MQ7

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2b76A (A:)
mqtfqadlaivgaggaglraaiaaaqanpnakialiskvypmrshtvaaqggsaavaqdh
dsfeyhfhdtvaggdwlceqdvvdyfvhhcptemtqlelwgcpwsrrpdgsvnvrrfggm
kiertwfaadktgfhmlhtlfqtslqfpqiqrfdehfvldilvddghvrglvamnmmegt
lvqiranavvmatggagrvyryntnggivtgdgmgmalshgvplrdmefvqyhptglpgs
gilmtegcrgeggilvnkngyrylqdygmgpetplgepknkymelgprdkvsqafwhewr
kgntistprgdvvyldlrhlgekklherlpficelakayvgvdpvkepipvrptahytmg
gietdqncetrikglfavgecssvglhganrlgsnslaelvvfgrlageqateraatagn
gneaaieaqaagveqrlkdlvnqdggenwakirdemglameegcgiyrtpelmqktidkl
aelqerfkrvritdtssvfntdllytielghglnvaecmahsamarkesrgahqrldegc
terddvnflkhtlafrdadgttrleysdvkittlppakrvyggeadaadkaeaankkeka
ng

    Sequence, based on observed residues (ATOM records): (download) 
    >2b76A (A:)
mqtfqadlaivgaggaglraaiaaaqanpnakialiskvypmrshtvaaqggsaavaqdh
dsfeyhfhdtvaggdwlceqdvvdyfvhhcptemtqlelwgcpwsrrpdgsvnvrrfggm
kiertwfaadktgfhmlhtlfqtslqfpqiqrfdehfvldilvddghvrglvamnmmegt
lvqiranavvmatggagrvyryntnggivtgdgmgmalshgvplrdmefvqyhptglpgs
gilmtegcrgeggilvnkngyrylqdygmgpetplgepknkymelgprdkvsqafwhewr
kgntistprgdvvyldlrhlgekklherlpficelakayvgvdpvkepipvrptahytmg
gietdqncetrikglfavgecssvglhganrlgsnslaelvvfgrlageqateraatagn
gneaaieaqaagveqrlkdlvnqdggenwakirdemglameegcgiyrtpelmqktidkl
aelqerfkrvritdtssvfntdllytielghglnvaecmahsamarkesrgahqrldegc
terddvnflkhtlafrdadgttrleysdvkittlppa

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2b76B (B:)
aemknlkievvrynpevdtaphsafyevpydattslldalgyikdnlapdlsyrwscrma
icgscgmmvnnvpklacktflrdytdgmkvealanfpierdlvvdmthfiesleaikpyi
ignsrtadqgtniqtpaqmakyhqfsgcincglcyaacpqfglnpefigpaaitlahryn
edsrdhgkkermaqlnsqngvwsctfvgycsevcpkhvdpaaaiqqgkvesskdfliatl
kpr

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2b76C (C:)
ttkrkpyvrpmtstwwkklpfyrfymlregtavpavwfsielifglfalkngpeawagfv
dflqnpviviinlitlaaallhtktwfelapkaaniivkdekmgpepiikslwavtvvat
ivilfvalyw

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2b76D (D:)
minpnpkrsdepvfwglfgaggmwsaiiapvmillvgillplglfpgdalsyervlafaq
sfigrvflflmivlplwcglhrmhhamhdlkihvpagkwvfyglaailtvvtligvvti

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >2b76M (M:)
mqtfqadlaivgaggaglraaiaaaqanpnakialiskvypmrshtvaaqggsaavaqdh
dsfeyhfhdtvaggdwlceqdvvdyfvhhcptemtqlelwgcpwsrrpdgsvnvrrfggm
kiertwfaadktgfhmlhtlfqtslqfpqiqrfdehfvldilvddghvrglvamnmmegt
lvqiranavvmatggagrvyryntnggivtgdgmgmalshgvplrdmefvqyhptglpgs
gilmtegcrgeggilvnkngyrylqdygmgpetplgepknkymelgprdkvsqafwhewr
kgntistprgdvvyldlrhlgekklherlpficelakayvgvdpvkepipvrptahytmg
gietdqncetrikglfavgecssvglhganrlgsnslaelvvfgrlageqateraatagn
gneaaieaqaagveqrlkdlvnqdggenwakirdemglameegcgiyrtpelmqktidkl
aelqerfkrvritdtssvfntdllytielghglnvaecmahsamarkesrgahqrldegc
terddvnflkhtlafrdadgttrleysdvkittlppakrvyggeadaadkaeaankkeka
ng

    Sequence, based on observed residues (ATOM records): (download) 
    >2b76M (M:)
mqtfqadlaivgaggaglraaiaaaqanpnakialiskvypmrshtvaaqggsaavaqdh
dsfeyhfhdtvaggdwlceqdvvdyfvhhcptemtqlelwgcpwsrrpdgsvnvrrfggm
kiertwfaadktgfhmlhtlfqtslqfpqiqrfdehfvldilvddghvrglvamnmmegt
lvqiranavvmatggagrvyryntnggivtgdgmgmalshgvplrdmefvqyhptglpgs
gilmtegcrgeggilvnkngyrylqdygmgpetplgepknkymelgprdkvsqafwhewr
kgntistprgdvvyldlrhlgekklherlpficelakayvgvdpvkepipvrptahytmg
gietdqncetrikglfavgecssvglhganrlgsnslaelvvfgrlageqateraatagn
gneaaieaqaagveqrlkdlvnqdggenwakirdemglameegcgiyrtpelmqktidkl
aelqerfkrvritdtssvfntdllytielghglnvaecmahsamarkesrgahqrldegc
terddvnflkhtlafrdadgttrleysdvkit

  • Chain 'N':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2b76N (N:)
aemknlkievvrynpevdtaphsafyevpydattslldalgyikdnlapdlsyrwscrma
icgscgmmvnnvpklacktflrdytdgmkvealanfpierdlvvdmthfiesleaikpyi
ignsrtadqgtniqtpaqmakyhqfsgcincglcyaacpqfglnpefigpaaitlahryn
edsrdhgkkermaqlnsqngvwsctfvgycsevcpkhvdpaaaiqqgkvesskdfliatl
kpr

  • Chain 'O':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2b76O (O:)
ttkrkpyvrpmtstwwkklpfyrfymlregtavpavwfsielifglfalkngpeawagfv
dflqnpviviinlitlaaallhtktwfelapkaaniivkdekmgpepiikslwavtvvat
ivilfvalyw

  • Chain 'P':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2b76P (P:)
minpnpkrsdepvfwglfgaggmwsaiiapvmillvgillplglfpgdalsyervlafaq
sfigrvflflmivlplwcglhrmhhamhdlkihvpagkwvfyglaailtvvtligvvti