PDB entry 2b52

View 2b52 on RCSB PDB site
Description: Human cyclin dependent kinase 2 (CDK2) complexed with DPH-042562
Class: transferase
Keywords: protein kinase, cell cycle, phosphorylation, cell division, mitosis, inhibition
Deposited on 2005-09-27, released 2005-10-11
The last revision prior to the SCOP 1.75 freeze date was dated 2005-10-11, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.88 Å
R-factor: 0.219
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: HOMO SAPIENS
    Gene: CDK2
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2b52a1
  • Heterogens: D42, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2b52A (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >2b52A (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirtegvpstaireisllkelnhpniv
    klldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvl
    hrdlkpqnllintegaikladfglahevvtlwyrapeillgckyystavdiwslgcifae
    mvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvvppl
    dedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl