PDB entry 2b3o

View 2b3o on RCSB PDB site
Description: Crystal structure of human tyrosine phosphatase SHP-1
Class: hydrolase
Keywords: Protein Tyrosine Phosphatase, SHP-1, Signaling, HYDROLASE
Deposited on 2005-09-20, released 2005-10-25
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.233
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein phosphatase, non-receptor type 6
    Species: Homo sapiens [TaxId:9606]
    Gene: PTPN6, HCP, PTP1C
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d2b3oa1, d2b3oa2, d2b3oa3
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2b3oA (A:)
mvrwfhrdlsgldaetllkgrgvhgsflarpsrknqgdfslsvrvgdqvthiriqnsgdf
ydlyggekfatltelveyytqqqgvlqdrdgtiihlkyplncsdptserwyhghmsggqa
etllqakgepwtflvreslsqpgdfvlsvlsdqpkagpgsplrvthikvmceggrytvgg
letfdsltdlvehfkktgieeasgafvylrqpyyatrvnaadienrvlelnkkqesedta
kagfweefeslqkqevknlhqrlegqrpenkgknryknilpfdhsrvilqgrdsnipgsd
yinanyiknqllgpdenaktyiasqgcleatvndfwqmawqensrvivmttrevekgrnk
cvpywpevgmqraygpysvtncgehdtteyklrtlqvspldngdlireiwhyqylswpdh
gvpsepggvlsfldqinqrqeslphagpiivhcsagigrtgtiividmlmenistkgldc
didiqktiqmvraqrsgmvqteaqykfiyvaiaqfiettkkklevlqsqkgq

    Sequence, based on observed residues (ATOM records): (download) 
    >2b3oA (A:)
vrwfhrdlsgldaetllkgrgvhgsflarpsrknqgdfslsvrvgdqvthiriqnsgdfy
dlyggekfatltelveyytqqqgvlqdrdgtiihlkyplncsdptserwyhghmsggqae
tllqakgepwtflvreslsqpgdfvlsvlsdqpksplrvthikvmceggrytvggletfd
sltdlvehfkktgieeasgafvylrqpyyatrvnaadienrfweefeslqkqevknlhqr
legqrpenkgknryknilpfdhsrvilqgrdsnipgsdyinanyiknqllgpdenaktyi
asqgcleatvndfwqmawqensrvivmttrevekgrnkcvpywpevgmqraygpysvtnc
gehdtteyklrtlqvspldngdlireiwhyqylswpdhgvpsepggvlsfldqinqrqes
lphagpiivhcsagigrtgtiividmlmenistkgldcdidiqktiqmvraqrsgmvqte
aqykfiyvaiaqfiettkkklevl