PDB entry 2ayo

View 2ayo on RCSB PDB site
Description: Structure of USP14 bound to ubquitin aldehyde
Class: hydrolase
Keywords: deubiquitinating enzyme, DUB, USP14, proteasome, enzyme mechanism
Deposited on 2005-09-07, released 2005-10-18
The last revision prior to the SCOP 1.73 freeze date was dated 2005-11-15, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 3.5 Å
R-factor: 0.29
AEROSPACI score: 0.03 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ubiquitin carboxyl-terminal hydrolase 14
    Species: HOMO SAPIENS
    Gene: USP14, TGT
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d2ayoa1
  • Chain 'B':
    Compound: Ubiquitin
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P62988 (0-75)
      • modified residue (75)
    Domains in SCOP 1.73: d2ayob1

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2ayoA (A:)
    dmteeqlasamelpcgltnlgntcymnatvqcirsvpelkdalkryagalrasgemasaq
    yitaalrdlfdsmdktsssippiillqflhmafpqfaekgeqgqylqqdanecwiqmmrv
    lqqkleaieddsvketdsssasaatpskkkslidqffgvefettmkcteseeeevtkgke
    nqlqlscfinqevkylftglklrlqeeitkqsptlqrnalyiksskisrlpayltiqmvr
    ffykekesvnakvlkdvkfplmldmyelctpelqekmvsfrskfkdledkkvnqqpntsd
    kksspqkevkyepfsfaddigsnncgyydlqavlthqgrssssghyvswvkrkqdewikf
    dddkvsivtpedilrlsgggdwhiayvllygprrveimeeeseq
    

    Sequence, based on observed residues (ATOM records): (download)
    >2ayoA (A:)
    asamelpcgltnlgntcymnatvqcirsvpelkdalkryagalrasgemasaqyitaalr
    dlfdsmdktsssippiillqflhmafpqfaekgeqgqylqqdanecwiqmmrvlqqklea
    ieddtpskkkslidqffgvefettmkcteseeeevtkgkenqlqlscfinqevkylftgl
    klrlqeeitkqsptlqrnalyiksskisrlpayltiqmvrffykekesvnakvlkdvkfp
    lmldmyelctpelqekmvsfrskfkdledevkyepfsfaddigsnncgyydlqavlthqg
    rssssghyvswvkrkqdewikfdddkvsivtpedilrlsgggdwhiayvllygpr
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >2ayoB (B:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrgg