PDB entry 2arp

View 2arp on RCSB PDB site
Description: Activin A in complex with Fs12 fragment of follistatin
Class: hormone/growth factor
Keywords: cystine knot, disulfide rich, egf domain, kazal domain, protein complex, HORMONE-GROWTH FACTOR COMPLEX
Deposited on 2005-08-21, released 2006-03-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.202
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Inhibin beta A chain
    Species: Homo sapiens [TaxId:9606]
    Gene: INHBA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2arpa_
  • Chain 'F':
    Compound: Follistatin
    Species: Rattus norvegicus [TaxId:10116]
    Gene: FST
    Database cross-references and differences (RAF-indexed):
  • Heterogens: NI, 1PG, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2arpA (A:)
glecdgkvnicckkqffvsfkdigwndwiiapsgyhanycegecpshiagtsgsslsfhs
tvinhyrmrghspfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs

    Sequence, based on observed residues (ATOM records): (download) 
    >2arpA (A:)
glecdgnicckkqffvsfkdigwndwiiapsgyhanycegecpslsfhstvinhyrmrgh
spfanlksccvptklrpmsmlyyddgqniikkdiqnmiveecgcs

  • Chain 'F':
    No sequence available.