PDB entry 2ajf

View 2ajf on RCSB PDB site
Description: Structure of SARS coronavirus spike receptor-binding domain complexed with its receptor
Class: hydrolase/viral protein
Keywords: antiparallel beta sheet, extended loop, hydrolase-viral protein COMPLEX
Deposited on 2005-08-01, released 2005-09-20
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.9 Å
R-factor: 0.221
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Angiotensin-converting enzyme-Related Carboxypeptidase (Ace2)
    Species: Homo sapiens [TaxId:9606]
    Gene: ACE2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2ajfa_
  • Chain 'B':
    Compound: Angiotensin-converting enzyme-Related Carboxypeptidase (Ace2)
    Species: Homo sapiens [TaxId:9606]
    Gene: ACE2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2ajfb_
  • Chain 'E':
    Compound: SARS-coronavirus spike protein
    Species: SARS coronavirus [TaxId:227859]
    Gene: S
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2ajfe1
  • Chain 'F':
    Compound: SARS-coronavirus spike protein
    Species: SARS coronavirus [TaxId:227859]
    Gene: S
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d2ajff_
  • Heterogens: NAG, ZN, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ajfA (A:)
stieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqst
laqmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpdnp
qeclllepglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyed
ygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyisp
igclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsv
glpnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemgh
iqydmayaaqpfllrnganegfheavgeimslsaatpkhlksigllspdfqedneteinf
llkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetyc
dpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnml
rlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspyad

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >2ajfB (B:)
stieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqst
laqmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpdnp
qeclllepglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyed
ygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyisp
igclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsv
glpnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemgh
iqydmayaaqpfllrnganegfheavgeimslsaatpkhlksigllspdfqedneteinf
llkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetyc
dpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnml
rlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspyad

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >2ajfE (E:)
cpfgevfnatkfpsvyawerkkisncvadysvlynstffstfkcygvsatklndlcfsnv
yadsfvvkgddvrqiapgqtgviadynyklpddfmgcvlawntrnidatstgnynykyry
lrhgklrpferdisnvpfspdgkpctppalncywplndygfytttgigyqpyrvvvlsfe

    Sequence, based on observed residues (ATOM records): (download) 
    >2ajfE (E:)
cpfgevfnatkfpsvyawerkkisncvadysvlynstffstfkcygvsatklnvyadsfv
vkgddvrqiapgqtgviadynyklpddfmgcvlawntrnidatstgnynykyrylrhgkl
rpferdisnvpfspdgkpctppalncywplndygfytttgigyqpyrvvvlsfe

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >2ajfF (F:)
cpfgevfnatkfpsvyawerkkisncvadysvlynstffstfkcygvsatklndlcfsnv
yadsfvvkgddvrqiapgqtgviadynyklpddfmgcvlawntrnidatstgnynykyry
lrhgklrpferdisnvpfspdgkpctppalncywplndygfytttgigyqpyrvvvlsfe

    Sequence, based on observed residues (ATOM records): (download) 
    >2ajfF (F:)
cpfgevfnatkfpsvyawerkkisncvadysvlynstffstfkcygvsatklnvyadsfv
vkgddvrqiapgqtgviadynyklpddfmgcvlawntrnidatstgnynykyrylrhgkl
rpferdisnvpfspdgkpctppalncywplndygfytttgigyqpyrvvvlsfe