PDB entry 2aeq

View 2aeq on RCSB PDB site
Description: An epidemiologically significant epitope of a 1998 influenza virus neuraminidase forms a highly hydrated interface in the NA-antibody complex.
Class: hydrolase/immune system
Keywords: influenza virus neuraminidase-fab complex, hydrolase-immune system complex
Deposited on 2005-07-23, released 2005-12-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 3 Å
R-factor: 0.267
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neuraminidase
    Species: Influenza A virus [TaxId:11320]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d2aeqa_
  • Chain 'H':
    Compound: Fab heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 2AEQ (0-End)
  • Chain 'L':
    Compound: Fab light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 2AEQ (0-End)
    Domains in SCOPe 2.07: d2aeql_
  • Heterogens: NAG, MAN

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2aeqA (A:)
    keicpklaeyrnwskpqckitgfapfskdnsirlsaggdiwvtrepyvscdpdkcyqfal
    gqgttlnnrhsndtvhdrtpyrtllmnelgvpfhlgtkqvciawsssschdgkawlhvcv
    tghdenatasfiydgrlvdsigswskkilrtqesecvcingtctvvmtdgsasgradtki
    lfieegkivhisplsgsaqhveecscyprypgvrcvcrdnwkgsnrpivdinvkdysivs
    syvcsglvgdtprkndssssshclnpnneegghgvkgwafddgndvwmgrtisekfrsgy
    etfkviegwskpnsklqinrqvivdrgnrsgysgifsvegkscinrcfyvelirgrkqet
    evwwtsnsivvfcgtsgtygtgswpdgadinlmpi
    

    Sequence, based on observed residues (ATOM records): (download)
    >2aeqA (A:)
    aeyrnwskpqckitgfapfskdnsirlsaggdiwvtrepyvscdpdkcyqfalgqgttln
    nrhsndtvhdrtpyrtllmnelgvpfhlgtkqvciawsssschdgkawlhvcvtghdena
    tasfiydgrlvdsigswskkilrtqesecvcingtctvvmtdgsasgradtkilfieegk
    ivhisplsgsaqhveecscyprypgvrcvcrdnwkgsnrpivdinvkdysivssyvcsgl
    vgdtprkndssssshclnpnneegghgvkgwafddgndvwmgrtisekfrsgyetfkvie
    gwskpnsklqinrqvivdrgnrsgysgifsvegkscinrcfyvelirgrkqetevwwtsn
    sivvfcgtsgtygtgswpdgadinlmpi
    

  • Chain 'H':
    No sequence available.

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >2aeqL (L:)
    dilmtqsqkflstsvgdrvsvtckasqnvgtnvawyqqkpgqspkplmysasyrysgvpd
    rftgsgsgtdftltisnvqsedlaeyfcqqfnrypltfgsgtklelkradaaptvsifpp
    sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
    ltkdeyerhnsytceathktstspivksfnrnec
    

    Sequence, based on observed residues (ATOM records): (download)
    >2aeqL (L:)
    dilmtqsqkflstsvgdrvsvtckasqnvgtnvawyqqkpgqspkplmysasyrysgvpd
    rftgsgsgtdftltisnvqsedlaeyfcqqfnrypltfgsgtklelk