PDB entry 2aeq

View 2aeq on RCSB PDB site
Description: An epidemiologically significant epitope of a 1998 influenza virus neuraminidase forms a highly hydrated interface in the NA-antibody complex.
Class: hydrolase/immune system
Keywords: influenza virus neuraminidase-fab complex, hydrolase-immune system complex
Deposited on 2005-07-23, released 2005-12-20
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neuraminidase
    Species: Influenza A virus [TaxId:11320]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d2aeqa_
  • Chain 'H':
    Compound: Fab heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 2AEQ (0-End)
    Domains in SCOPe 2.08: d2aeqh_
  • Chain 'L':
    Compound: Fab light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 2AEQ (0-End)
    Domains in SCOPe 2.08: d2aeql_
  • Heterogens: NAG, MAN

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2aeqA (A:)
keicpklaeyrnwskpqckitgfapfskdnsirlsaggdiwvtrepyvscdpdkcyqfal
gqgttlnnrhsndtvhdrtpyrtllmnelgvpfhlgtkqvciawsssschdgkawlhvcv
tghdenatasfiydgrlvdsigswskkilrtqesecvcingtctvvmtdgsasgradtki
lfieegkivhisplsgsaqhveecscyprypgvrcvcrdnwkgsnrpivdinvkdysivs
syvcsglvgdtprkndssssshclnpnneegghgvkgwafddgndvwmgrtisekfrsgy
etfkviegwskpnsklqinrqvivdrgnrsgysgifsvegkscinrcfyvelirgrkqet
evwwtsnsivvfcgtsgtygtgswpdgadinlmpi

    Sequence, based on observed residues (ATOM records): (download) 
    >2aeqA (A:)
aeyrnwskpqckitgfapfskdnsirlsaggdiwvtrepyvscdpdkcyqfalgqgttln
nrhsndtvhdrtpyrtllmnelgvpfhlgtkqvciawsssschdgkawlhvcvtghdena
tasfiydgrlvdsigswskkilrtqesecvcingtctvvmtdgsasgradtkilfieegk
ivhisplsgsaqhveecscyprypgvrcvcrdnwkgsnrpivdinvkdysivssyvcsgl
vgdtprkndssssshclnpnneegghgvkgwafddgndvwmgrtisekfrsgyetfkvie
gwskpnsklqinrqvivdrgnrsgysgifsvegkscinrcfyvelirgrkqetevwwtsn
sivvfcgtsgtygtgswpdgadinlmpi

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2aeqH (H:)
evklvesggglvqpggslslscatsgftfidyymswfrqppgkalewlglirnkgngytm
eysaslkgrftisrdnsqsivylhmntltaedsatyycarvdygtnydywgqgttltvss
akttapsvyplapvcgdttgssvtlgclvkgyfpepvtltwnsgslssgvhtfpavlqsd
lytlsssvtvtsstwpsqsitcnvahpasstkvdkki

    Sequence, based on observed residues (ATOM records): (download) 
    >2aeqH (H:)
evklvesggglvqpggslslscatsgftfidyymswfrqppgkalewlglirnkgngytm
eysaslkgrftisrdnsqsivylhmntltaedsatyycarvdygtnydywgqgttl

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >2aeqL (L:)
dilmtqsqkflstsvgdrvsvtckasqnvgtnvawyqqkpgqspkplmysasyrysgvpd
rftgsgsgtdftltisnvqsedlaeyfcqqfnrypltfgsgtklelkradaaptvsifpp
sseqltsggasvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstysmsstlt
ltkdeyerhnsytceathktstspivksfnrnec

    Sequence, based on observed residues (ATOM records): (download) 
    >2aeqL (L:)
dilmtqsqkflstsvgdrvsvtckasqnvgtnvawyqqkpgqspkplmysasyrysgvpd
rftgsgsgtdftltisnvqsedlaeyfcqqfnrypltfgsgtklelk