PDB entry 2aep

View 2aep on RCSB PDB site
Description: An epidemiologically significant epitope of a 1998 influenza virus neuraminidase forms a highly hydrated interface in the NA-antibody complex.
Class: immune system
Keywords: influenza virus neuraminidase-fab complex
Deposited on 2005-07-23, released 2005-12-20
The last revision prior to the SCOP 1.75 freeze date was dated 2006-02-14, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: 0.19
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neuraminidase
    Species: influenza virus
    Database cross-references and differences (RAF-indexed):
    • GB AAP23239 (Start-394)
    Domains in SCOP 1.75: d2aepa1
  • Chain 'H':
    Compound: Fab heavy chain
    Species: MUS MUSCULUS
    Domains in SCOP 1.75: d2aeph1
  • Chain 'L':
    Compound: Fab light chain
    Species: MUS MUSCULUS
  • Heterogens: GLC, NAG, MAN, CA, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2aepA (A:)
keicpklaeyrnwskpqckitgfapfskdnsirlsaggdiwvtrepyvscdpdkcyqfal
gqgttlnnrhsndtvhdrtpyrtllmnelgvpfhlgtkqvciawsssschdgkawlhvcv
tghdenatasfiydgrlvdsigswskkilrtqesecvcingtctvvmtdgsasgradtki
lfieegkivhisplsgsaqhveecscyprypgvrcvcrdnwkgsnrpivdinvkdysivs
syvcsglvgdtprkndssssshclnpnneegghgvkgwafddgndvwmgrtisekfrsgy
etfkviegwskpnsklqinrqvivdrgnrsgysgifsvegkscinrcfyvelirgrkqet
evwwtsnsivvfcgtsgtygtgswpdgadinlmpi

    Sequence, based on observed residues (ATOM records): (download) 
    >2aepA (A:)
aeyrnwskpqckitgfapfskdnsirlsaggdiwvtrepyvscdpdkcyqfalgqgttln
nrhsndtvhdrtpyrtllmnelgvpfhlgtkqvciawsssschdgkawlhvcvtghdena
tasfiydgrlvdsigswskkilrtqesecvcingtctvvmtdgsasgradtkilfieegk
ivhisplsgsaqhveecscyprypgvrcvcrdnwkgsnrpivdinvkdysivssyvcsgl
vgdtprkndssssshclnpnneegghgvkgwafddgndvwmgrtisekfrsgyetfkvie
gwskpnsklqinrqvivdrgnrsgysgifsvegkscinrcfyvelirgrkqetevwwtsn
sivvfcgtsgtygtgswpdgadinlmpi

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >2aepH (H:)
evklvesggglvqpggslslscatsgftfidyymswfrqppgkalewlglirnkgngytm
eysaslkgrftisrdnsqsivylhmntltaedsatyycarvdygtnydywgqgttltvss
akttapsvyplapvcgdttgssvtlgclvkgyfpepvtltwnsgslssgvhtfpavlqsd
lytlsssvtvtsstwpsqsitcnvahpasstkvdkki

    Sequence, based on observed residues (ATOM records): (download) 
    >2aepH (H:)
evklvesggglvqpggslslscatsgftfidyymswfrqppgkalewlglirnkgngytm
eysaslkgrftisrdnsqsivylhmntltaedsatyycarvdygtnydywgqgttltvss
aktfpepvtltgvhtfpatlsss

  • Chain 'L':
    No sequence available.