PDB entry 2a4l

View 2a4l on RCSB PDB site
Description: Human cyclin-dependent kinase 2 in complex with roscovitine
Class: transferase
Keywords: transferase, serine/threonine protein kinase, ATP-binding, cell cycle, cell division, roscovitine, phosphorylation
Deposited on 2005-06-29, released 2006-10-03
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Homo sapiens cyclin-dependent kinase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • GB AAP36159 (0-297)
    Domains in SCOPe 2.07: d2a4la_
  • Heterogens: RRC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >2a4lA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >2a4lA (A:)
    menfqkvekigegtygvvykarnkltgevvalkkiaireisllkelnhpnivklldviht
    enklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrdlkpqn
    llintegaikladfglarafgvpvrtythevvtlwyrapeillgckyystavdiwslgci
    faemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvv
    ppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl