PDB entry 2a4f

View 2a4f on RCSB PDB site
Description: Synthesis and Activity of N-Axyl Azacyclic Urea HIV-1 Protease Inhibitors with High Potency Against Multiple Drug Resistant Viral Strains.
Class: hydrolase
Keywords: HIV protease, aza-cyclic urea
Deposited on 2005-06-28, released 2005-09-20
The last revision prior to the SCOP 1.73 freeze date was dated 2005-11-22, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.298
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Pol polyprotein
  Species: Human immunodeficiency virus 1
  Gene: pol
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q9Q2G8 (0-98)
  Domains in SCOP 1.73: d2a4fa1
• Chain 'B':
  Compound: Pol polyprotein
  Species: Human immunodeficiency virus 1
  Gene: pol
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q9Q2G8 (0-98)
  Domains in SCOP 1.73: d2a4fb1
• Heterogens: AAU, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2a4fA (A:)
  pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
  qilieicghkaigtvlvgptpvniigrnlltqigctlnf
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >2a4fB (B:)
  pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
  qilieicghkaigtvlvgptpvniigrnlltqigctlnf