PDB entry 2a0c

View 2a0c on RCSB PDB site
Description: Human CDK2 in complex with olomoucine II, a novel 2,6,9-trisubstituted purine cyclin-dependent kinase inhibitor
Class: transferase
Keywords: protein kinase, cell cycle, phosphorylation, cell division,mitosis, inhibition, transferase, serine/threonine-protein kinase, ATP-binding, 3d-structure
Deposited on 2005-06-16, released 2006-01-24
The last revision prior to the SCOP 1.75 freeze date was dated 2006-01-24, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.194
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'X':
    Compound: Cell division protein kinase 2
    Species: HOMO SAPIENS
    Gene: CDK2
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d2a0cx1
  • Heterogens: CK9, HOH

PDB Chain Sequences:

  • Chain 'X':
    Sequence, based on SEQRES records: (download) 
    >2a0cX (X:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

    Sequence, based on observed residues (ATOM records): (download) 
    >2a0cX (X:)
menfqkvekigegtygvvykarnkltgevvalkkirtegvpstaireisllkelnhpniv
klldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvl
hrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyystav
diwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwa
rqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl