PDB entry 1zys
View 1zys on RCSB PDB site
Description: Co-crystal structure of Checkpoint Kinase Chk1 with a pyrrolo-pyridine inhibitor
Class: signaling protein, transferase
Keywords: Chk1; Crystal structure, SIGNALING PROTEIN, TRANSFERASE
Deposited on
2005-06-10, released
2006-06-13
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-10-11, with a file datestamp of
2017-10-06.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.4
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Serine/threonine-protein kinase Chk1
Species: Homo sapiens [TaxId:9606]
Gene: CHEK1, CHK1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1zysa_ - Chain 'B':
Compound: pentapeptide fragment
Database cross-references and differences (RAF-indexed):
- Heterogens: SO4, 199, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1zysA (A:)
mavpfvedwdlvqtlgegaygevqlavnrvteeavavkivdmkravdcpenikkeicina
mlnhenvvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvy
lhgigithrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellk
rrefhaepvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsapla
llhkilvenpsaritipdikkdrwynkplkkga
Sequence, based on observed residues (ATOM records): (download)
>1zysA (A:)
vpfvedwdlvqtlgegaygevqlavnrvteeavavkivdmkravdcpenikkeicinaml
nhenvvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylh
gigithrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrr
efhaepvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplall
hkilvenpsaritipdikkdrwynkplkkga
- Chain 'B':
No sequence available.