PDB entry 1zli

View 1zli on RCSB PDB site
Description: Crystal structure of the tick carboxypeptidase inhibitor in complex with human carboxypeptidase B
Class: hydrolase/hydrolase inhibitor
Keywords: inhibitor-metallocarboxypeptidase complex, beta-defensin fold (TCI), eight-stranded twisted beta-sheet surrounded by eight alpha-helices (CPB)
Deposited on 2005-05-06, released 2005-07-05
The last revision prior to the SCOP 1.75 freeze date was dated 2005-07-05, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.09 Å
R-factor: 0.16
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: carboxypeptidase b
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P15086 (Start-308)
      • conflict (12)
      • conflict (99)
    Domains in SCOP 1.75: d1zlia1
  • Chain 'B':
    Compound: carboxypeptidase inhibitor
    Species: Rhipicephalus bursa
    Database cross-references and differences (RAF-indexed):
    • GB AAW72225 (0-End)
    Domains in SCOP 1.75: d1zlib1, d1zlib2
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1zliA (A:)
    vratghsyekynnwetieawtqqvatenpalisrsvigttfegraiyllkvgkagqnkpa
    ifmdcgfharewispafcqwfvreavrtygreiqvtellnkldfyvlpvlnidgyiytwt
    ksrfwrktrsthtgsscigtdpnrnfdagwceigasrnpcdetycgpaaeseketkalad
    firnklssikayltihsysqmmiypysyayklgennaelnalakatvkelaslhgtkyty
    gpgattiypaaggsddwaydqgirysftfelrdtgrygfllpesqiratceetflaikyv
    asyvlehly
    

    Sequence, based on observed residues (ATOM records): (download)
    >1zliA (A:)
    tghsyekynnwetieawtqqvatenpalisrsvigttfegraiyllkvgkagqnkpaifm
    dcgfharewispafcqwfvreavrtygreiqvtellnkldfyvlpvlnidgyiytwtksr
    fwrktrsthtgsscigtdpnrnfdagwceigasrnpcdetycgpaaeseketkaladfir
    nklssikayltihsysqmmiypysyayklgennaelnalakatvkelaslhgtkytygpg
    attiypaaggsddwaydqgirysftfelrdtgrygfllpesqiratceetflaikyvasy
    vlehly
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1zliB (B:)
    necvskgfgclpqsdcpqearlsyggcstvccdlskltgckgkggecnpldrqckelqae
    sascgkgqkccvwlh
    

    Sequence, based on observed residues (ATOM records): (download)
    >1zliB (B:)
    necvskgfgclpqsdcpqearlsyggcstvccdlskltgckgkggecnpldrqckelqae
    sascgkgqkccvwl