PDB entry 1z7x

View 1z7x on RCSB PDB site
Description: X-ray structure of human ribonuclease inhibitor complexed with ribonuclease I
Class: Hydrolase/Hydrolase INHIBITOR
Keywords: RIBONUCLEASE-INHIBITOR COMPLEX, LEUCINE-RICH REPEAT, ENZYME-INHIBITOR COMPLEX, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, CESG, Center for Eukaryotic Structural Genomics
Deposited on 2005-03-28, released 2005-06-21
The last revision prior to the SCOP 1.73 freeze date was dated 2006-04-25, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.178
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'W':
    Compound: ribonuclease inhibitor
    Species: HOMO SAPIENS
    Gene: RNH, PRI
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1z7xw1
  • Chain 'X':
    Compound: Ribonuclease I
    Species: HOMO SAPIENS
    Gene: RNASE1, RIB1, RNS1
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1z7xx1
  • Chain 'Y':
    Compound: ribonuclease inhibitor
    Species: HOMO SAPIENS
    Gene: RNH, PRI
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1z7xy1
  • Chain 'Z':
    Compound: Ribonuclease I
    Species: HOMO SAPIENS
    Gene: RNASE1, RIB1, RNS1
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1z7xz1
  • Heterogens: CIT, HOH

PDB Chain Sequences:

  • Chain 'W':
    Sequence, based on SEQRES records: (download)
    >1z7xW (W:)
    msldiqsldiqceelsdarwaellpllqqcqvvrlddcgltearckdissalrvnpalae
    lnlrsnelgdvgvhcvlqglqtpsckiqklslqnccltgagcgvlsstlrtlptlqelhl
    sdnllgdaglqllceglldpqcrleklqleycslsaasceplasvlrakpdfkeltvsnn
    dineagvrvlcqglkdspcqlealklescgvtsdncrdlcgivaskaslrelalgsnklg
    dvgmaelcpgllhpssrlrtlwiwecgitakgcgdlcrvlrakeslkelslagnelgdeg
    arllcetllepgcqleslwvkscsftaaccshfssvlaqnrfllelqisnnrledagvre
    lcqglgqpgsvlrvlwladcdvsdsscsslaatllanhslreldlsnnclgdagilqlve
    svrqpgclleqlvlydiywseemedrlqalekdkpslrvis
    

    Sequence, based on observed residues (ATOM records): (download)
    >1z7xW (W:)
    sldiqsldiqceelsdarwaellpllqqcqvvrlddcgltearckdissalrvnpalael
    nlrsnelgdvgvhcvlqglqtpsckiqklslqnccltgagcgvlsstlrtlptlqelhls
    dnllgdaglqllceglldpqcrleklqleycslsaasceplasvlrakpdfkeltvsnnd
    ineagvrvlcqglkdspcqlealklescgvtsdncrdlcgivaskaslrelalgsnklgd
    vgmaelcpgllhpssrlrtlwiwecgitakgcgdlcrvlrakeslkelslagnelgdega
    rllcetllepgcqleslwvkscsftaaccshfssvlaqnrfllelqisnnrledagvrel
    cqglgqpgsvlrvlwladcdvsdsscsslaatllanhslreldlsnnclgdagilqlves
    vrqpgclleqlvlydiywseemedrlqalekdkpslrvis
    

  • Chain 'X':
    Sequence, based on SEQRES records: (download)
    >1z7xX (X:)
    mkesrakkfqrqhmdsdsspsssstycnqmmrrrnmtqgrckpvntfvheplvdvqnvcf
    qekvtckngqgncyksnssmhitdcrltngsrypncayrtspkerhiivacegspyvpvh
    fdasvedst
    

    Sequence, based on observed residues (ATOM records): (download)
    >1z7xX (X:)
    esrakkfqrqhmdsdsspsssstycnqmmrrrnmtqgrckpvntfvheplvdvqnvcfqe
    kvtckngqgncyksnssmhitdcrltngsrypncayrtspkerhiivacegspyvpvhfd
    asveds
    

  • Chain 'Y':
    Sequence, based on SEQRES records: (download)
    >1z7xY (Y:)
    msldiqsldiqceelsdarwaellpllqqcqvvrlddcgltearckdissalrvnpalae
    lnlrsnelgdvgvhcvlqglqtpsckiqklslqnccltgagcgvlsstlrtlptlqelhl
    sdnllgdaglqllceglldpqcrleklqleycslsaasceplasvlrakpdfkeltvsnn
    dineagvrvlcqglkdspcqlealklescgvtsdncrdlcgivaskaslrelalgsnklg
    dvgmaelcpgllhpssrlrtlwiwecgitakgcgdlcrvlrakeslkelslagnelgdeg
    arllcetllepgcqleslwvkscsftaaccshfssvlaqnrfllelqisnnrledagvre
    lcqglgqpgsvlrvlwladcdvsdsscsslaatllanhslreldlsnnclgdagilqlve
    svrqpgclleqlvlydiywseemedrlqalekdkpslrvis
    

    Sequence, based on observed residues (ATOM records): (download)
    >1z7xY (Y:)
    sldiqsldiqceelsdarwaellpllqqcqvvrlddcgltearckdissalrvnpalael
    nlrsnelgdvgvhcvlqglqtpsckiqklslqnccltgagcgvlsstlrtlptlqelhls
    dnllgdaglqllceglldpqcrleklqleycslsaasceplasvlrakpdfkeltvsnnd
    ineagvrvlcqglkdspcqlealklescgvtsdncrdlcgivaskaslrelalgsnklgd
    vgmaelcpgllhpssrlrtlwiwecgitakgcgdlcrvlrakeslkelslagnelgdega
    rllcetllepgcqleslwvkscsftaaccshfssvlaqnrfllelqisnnrledagvrel
    cqglgqpgsvlrvlwladcdvsdsscsslaatllanhslreldlsnnclgdagilqlves
    vrqpgclleqlvlydiywseemedrlqalekdkpslrvis
    

  • Chain 'Z':
    Sequence, based on SEQRES records: (download)
    >1z7xZ (Z:)
    mkesrakkfqrqhmdsdsspsssstycnqmmrrrnmtqgrckpvntfvheplvdvqnvcf
    qekvtckngqgncyksnssmhitdcrltngsrypncayrtspkerhiivacegspyvpvh
    fdasvedst
    

    Sequence, based on observed residues (ATOM records): (download)
    >1z7xZ (Z:)
    esrakkfqrqhmdsdsspsssstycnqmmrrrnmtqgrckpvntfvheplvdvqnvcfqe
    kvtckngqgncyksnssmhitdcrltngsrypncayrtspkerhiivacegspyvpvhfd
    asveds