PDB entry 1yql

View 1yql on RCSB PDB site
Description: Catalytically inactive hOGG1 crosslinked with 7-deaza-8-azaguanine containing DNA
Class: hydrolase/DNA
Keywords: disulfide crosslinking, hydrolase/DNA complex
Deposited on 2005-02-02, released 2005-04-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.213
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: N-glycosylase/DNA lyase
    Species: Homo sapiens [TaxId:9606]
    Gene: OGG1, MMH, MUTM, OGH1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O15527 (3-End)
      • cloning artifact (0-2)
      • engineered (140)
      • engineered (240)
    Domains in SCOPe 2.08: d1yqla1, d1yqla2, d1yqla3
  • Chain 'B':
    Compound: 5'-d(p*gp*gp*tp*ap*gp*ap*cp*cp*tp*gp*gp*ap*c)-3'
  • Chain 'C':
    Compound: 5'-d(p*gp*tp*cp*cp*ap*(ppw)p*gp*tp*cp*tp*ap*c)-3'
  • Heterogens: CA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1yqlA (A:)
sefghrtlastpalwasipcprselrldlvlpsgqsfrwreqspahwsgvladqvwtltq
teeqlhctvyrgdksqasrptpdeleavrkyfqldvtlaqlyhhwgsvdshfqevaqkfq
gvrllrqdpieclfsficsscnniaritgmverlcqafgprliqlddvtyhgfpslqala
gpeveahlrklglgyraryvsasaraileeqgglawlqqlressyeeahkalcilpgvgt
qvadciclmaldkpqavpvdvhmwhiaqrdyswhpttsqakgpspqtnkelgnffrslwg
pyagwaqavlfsadlrqsr

    Sequence, based on observed residues (ATOM records): (download) 
    >1yqlA (A:)
sefghrtlastpalwasipcprselrldlvlpsgqsfrwreqspahwsgvladqvwtltq
teeqlhctvyrsqasrptpdeleavrkyfqldvtlaqlyhhwgsvdshfqevaqkfqgvr
llrqdpieclfsficsscnniaritgmverlcqafgprliqlddvtyhgfpslqalagpe
veahlrklglgyraryvsasaraileeqgglawlqqlressyeeahkalcilpgvgtqva
dciclmaldkpqavpvdvhmwhiaqrdyswhpttsqakgpspqtnkelgnffrslwgpya
gwaqavlfsadlrq

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.