PDB entry 1yqj

View 1yqj on RCSB PDB site
Description: Crystal Structure of p38 Alpha in Complex with a Selective Pyridazine Inhibitor
Class: transferase
Keywords: transferase
Deposited on 2005-02-01, released 2005-04-26
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.205
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 14
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPK14, CSBP, CSBP1, CSBP2, MXI2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16539 (7-End)
      • cloning artifact (2-6)
    Domains in SCOPe 2.01: d1yqja_
  • Heterogens: SO4, 6NP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1yqjA (A:)
gshmlemsqerptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkk
lsrpfqsiihakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadln
nivkcqkltddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarh
tddemtgyvatrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlkl
ilrlvgtpgaellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsd
kritaaqalahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppld
qeemes

    Sequence, based on observed residues (ATOM records): (download) 
    >1yqjA (A:)
hmlemsqerptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktglrvavkkls
rpfqsiihakrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnni
vkcqkltddhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtd
demtgyvatrwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklil
rlvgtpgaellkkissesarnyiqsltqmpkmnfanvfiganplavdllekmlvldsdkr
itaaqalahayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvppp