PDB entry 1you

View 1you on RCSB PDB site
Description: Crystal structure of the catalytic domain of MMP-13 complexed with a potent pyrimidinetrione inhibitor
Class: hydrolase
Keywords: hydrolase, metalloprotease
Deposited on 2005-01-28, released 2005-03-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.215
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: collagenase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: MMP13
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1youa_
  • Chain 'B':
    Compound: collagenase 3
    Species: Homo sapiens [TaxId:9606]
    Gene: MMP13
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1youb_
  • Heterogens: ZN, CA, SO4, PFD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1youA (A:)
ynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
fghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygpgde

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1youB (B:)
ynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
fghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygpgde

    Sequence, based on observed residues (ATOM records): (download) 
    >1youB (B:)
ynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
fghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygp