PDB entry 1ym7

View 1ym7 on RCSB PDB site
Description: G Protein-Coupled Receptor Kinase 2 (GRK2)
Class: transferase
Keywords: G protein, kinase, GPCR, GRK2, Beta-ARK1
Deposited on 2005-01-20, released 2005-07-05
The last revision prior to the SCOP 1.73 freeze date was dated 2005-07-05, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 4.5 Å
R-factor: 0.226
AEROSPACI score: 0.07 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-adrenergic receptor kinase 1
    Species: BOS TAURUS
    Gene: ADRBK1, GRK2
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1ym7a1, d1ym7a2, d1ym7a3
  • Chain 'B':
    Compound: Beta-adrenergic receptor kinase 1
    Species: BOS TAURUS
    Gene: ADRBK1, GRK2
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1ym7b1, d1ym7b2, d1ym7b3
  • Chain 'C':
    Compound: Beta-adrenergic receptor kinase 1
    Species: BOS TAURUS
    Gene: ADRBK1, GRK2
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1ym7c1, d1ym7c2, d1ym7c3
  • Chain 'D':
    Compound: Beta-adrenergic receptor kinase 1
    Species: BOS TAURUS
    Gene: ADRBK1, GRK2
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1ym7d1, d1ym7d2, d1ym7d3

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ym7A (A:)
madleavladvsylmamekskatpaaraskkillpepsirsvmqkyledrgevtfekifs
qklgyllfrdfclkhleeakplvefyeeikkyekleteeerlvcsreifdtyimkellac
shpfsksaiehvqghlvkkqvppdlfqpyieeicqnlrgdvfqkfiesdkftrfcqwknv
elnihltmndfsvhriigrggfgevygcrkadtgkmyamkcldkkrikmkqgetlalner
imlslvstgdcpfivcmsyafhtpdklsfildlmnggdlhyhlsqhgvfseadmrfyaae
iilglehmhnrfvvyrdlkpanilldehghvrisdlglacdfskkkphasvgthgymape
vlqkgvaydssadwfslgcmlfkllrghspfrqhktkdkheidrmtltmavelpdsfspe
lrsllegllqrdvnrrlgclgrgaqevkespffrsldwqmvflqkyppplipprgevnaa
dafdigsfdeedtkgiklldsdqelyrnfpltiserwqqevaetvfdtinaetdrleark
ktknkqlgheedyalgkdcimhgymskmgnpfltqwqrryfylfpnrlewrgegeapqsl
ltmeeiqsveetqikerkclllkirggkqfvlqcdsdpelvqwkkelrdayreaqqlvqr
vpkmknkprapvvelskvpliqrgsangl

    Sequence, based on observed residues (ATOM records): (download) 
    >1ym7A (A:)
skkillpepsirsvmqkyledrgevtfekifsqklgyllfrdfclkhleeakplvefyee
ikkyekleteeerlvcsreifdtyimkellacshpfsksaiehvqghlvkkqvppdlfqp
yieeicqnlrgdvfqkfiesdkftrfcqwknvelnihltmndfsvhriigrggfgevygc
rkadtgkmyamkcldkkrikmkqgetlalnerimlslvstgdcpfivcmsyafhtpdkls
fildlmnggdlhyhlsqhgvfseadmrfyaaeiilglehmhnrfvvyrdlkpanilldeh
ghvrisdlglacdfskkkphasvgthgymapevlqkgvaydssadwfslgcmlfkllrgh
spfrqhktkdkheidrmtltmavelpdsfspelrsllegllqrdvnrrlgclgrgaqevk
espffrsldwqmvflqkyppplipprgtkgiklldsdqelyrnfpltiserwqqevaetv
fdtinaetdrlearkktknkqlgheedyalgkdcimhgymskmgntqwqrryfylfpnrl
ewrgegeapqslltmeeiqsveetqikerkclllkirggkqfvlqcdsdpelvqwkkelr
dayreaqq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1ym7B (B:)
madleavladvsylmamekskatpaaraskkillpepsirsvmqkyledrgevtfekifs
qklgyllfrdfclkhleeakplvefyeeikkyekleteeerlvcsreifdtyimkellac
shpfsksaiehvqghlvkkqvppdlfqpyieeicqnlrgdvfqkfiesdkftrfcqwknv
elnihltmndfsvhriigrggfgevygcrkadtgkmyamkcldkkrikmkqgetlalner
imlslvstgdcpfivcmsyafhtpdklsfildlmnggdlhyhlsqhgvfseadmrfyaae
iilglehmhnrfvvyrdlkpanilldehghvrisdlglacdfskkkphasvgthgymape
vlqkgvaydssadwfslgcmlfkllrghspfrqhktkdkheidrmtltmavelpdsfspe
lrsllegllqrdvnrrlgclgrgaqevkespffrsldwqmvflqkyppplipprgevnaa
dafdigsfdeedtkgiklldsdqelyrnfpltiserwqqevaetvfdtinaetdrleark
ktknkqlgheedyalgkdcimhgymskmgnpfltqwqrryfylfpnrlewrgegeapqsl
ltmeeiqsveetqikerkclllkirggkqfvlqcdsdpelvqwkkelrdayreaqqlvqr
vpkmknkprapvvelskvpliqrgsangl

    Sequence, based on observed residues (ATOM records): (download) 
    >1ym7B (B:)
skkillpepsirsvmqkyledrgevtfekifsqklgyllfrdfclkhleeakplvefyee
ikkyekleteeerlvcsreifdtyimkellacshpfsksaiehvqghlvkkqvppdlfqp
yieeicqnlrgdvfqkfiesdkftrfcqwknvelnihltmndfsvhriigrggfgevygc
rkadtgkmyamkcldkkrikmkqgetlalnerimlslvstgdcpfivcmsyafhtpdkls
fildlmnggdlhyhlsqhgvfseadmrfyaaeiilglehmhnrfvvyrdlkpanilldeh
ghvrisdlglacdfskkkphasvgthgymapevlqkgvaydssadwfslgcmlfkllrgh
spfrqhktkdkheidrmtltmavelpdsfspelrsllegllqrdvnrrlgclgrgaqevk
espffrsldwqmvflqkyppplipprgtkgiklldsdqelyrnfpltiserwqqevaetv
fdtinaetdrlearkktknkqlgheedyalgkdcimhgymskmgntqwqrryfylfpnrl
ewrgegeapqslltmeeiqsveetqikerkclllkirggkqfvlqcdsdpelvqwkkelr
dayreaqq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1ym7C (C:)
madleavladvsylmamekskatpaaraskkillpepsirsvmqkyledrgevtfekifs
qklgyllfrdfclkhleeakplvefyeeikkyekleteeerlvcsreifdtyimkellac
shpfsksaiehvqghlvkkqvppdlfqpyieeicqnlrgdvfqkfiesdkftrfcqwknv
elnihltmndfsvhriigrggfgevygcrkadtgkmyamkcldkkrikmkqgetlalner
imlslvstgdcpfivcmsyafhtpdklsfildlmnggdlhyhlsqhgvfseadmrfyaae
iilglehmhnrfvvyrdlkpanilldehghvrisdlglacdfskkkphasvgthgymape
vlqkgvaydssadwfslgcmlfkllrghspfrqhktkdkheidrmtltmavelpdsfspe
lrsllegllqrdvnrrlgclgrgaqevkespffrsldwqmvflqkyppplipprgevnaa
dafdigsfdeedtkgiklldsdqelyrnfpltiserwqqevaetvfdtinaetdrleark
ktknkqlgheedyalgkdcimhgymskmgnpfltqwqrryfylfpnrlewrgegeapqsl
ltmeeiqsveetqikerkclllkirggkqfvlqcdsdpelvqwkkelrdayreaqqlvqr
vpkmknkprapvvelskvpliqrgsangl

    Sequence, based on observed residues (ATOM records): (download) 
    >1ym7C (C:)
skkillpepsirsvmqkyledrgevtfekifsqklgyllfrdfclkhleeakplvefyee
ikkyekleteeerlvcsreifdtyimkellacshpfsksaiehvqghlvkkqvppdlfqp
yieeicqnlrgdvfqkfiesdkftrfcqwknvelnihltmndfsvhriigrggfgevygc
rkadtgkmyamkcldkkrikmkqgetlalnerimlslvstgdcpfivcmsyafhtpdkls
fildlmnggdlhyhlsqhgvfseadmrfyaaeiilglehmhnrfvvyrdlkpanilldeh
ghvrisdlglacdfskkkphasvgthgymapevlqkgvaydssadwfslgcmlfkllrgh
spfrqhktkdkheidrmtltmavelpdsfspelrsllegllqrdvnrrlgclgrgaqevk
espffrsldwqmvflqkyppplipprgkgiklldsdqelyrnfpltiserwqqevaetvf
dtinaetdrlearkktknkqlgheedyalgkdcimhgymskmgntqwqrryfylfpnrle
wrgegeapqslltmeeiqsveetqikerkclllkirggkqfvlqcdsdpelvqwkkelrd
ayreaqq

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1ym7D (D:)
madleavladvsylmamekskatpaaraskkillpepsirsvmqkyledrgevtfekifs
qklgyllfrdfclkhleeakplvefyeeikkyekleteeerlvcsreifdtyimkellac
shpfsksaiehvqghlvkkqvppdlfqpyieeicqnlrgdvfqkfiesdkftrfcqwknv
elnihltmndfsvhriigrggfgevygcrkadtgkmyamkcldkkrikmkqgetlalner
imlslvstgdcpfivcmsyafhtpdklsfildlmnggdlhyhlsqhgvfseadmrfyaae
iilglehmhnrfvvyrdlkpanilldehghvrisdlglacdfskkkphasvgthgymape
vlqkgvaydssadwfslgcmlfkllrghspfrqhktkdkheidrmtltmavelpdsfspe
lrsllegllqrdvnrrlgclgrgaqevkespffrsldwqmvflqkyppplipprgevnaa
dafdigsfdeedtkgiklldsdqelyrnfpltiserwqqevaetvfdtinaetdrleark
ktknkqlgheedyalgkdcimhgymskmgnpfltqwqrryfylfpnrlewrgegeapqsl
ltmeeiqsveetqikerkclllkirggkqfvlqcdsdpelvqwkkelrdayreaqqlvqr
vpkmknkprapvvelskvpliqrgsangl

    Sequence, based on observed residues (ATOM records): (download) 
    >1ym7D (D:)
skkillpepsirsvmqkyledrgevtfekifsqklgyllfrdfclkhleeakplvefyee
ikkyekleteeerlvcsreifdtyimkellacshpfsksaiehvqghlvkkqvppdlfqp
yieeicqnlrgdvfqkfiesdkftrfcqwknvelnihltmndfsvhriigrggfgevygc
rkadtgkmyamkcldkkrikmkqgetlalnerimlslvstgdcpfivcmsyafhtpdkls
fildlmnggdlhyhlsqhgvfseadmrfyaaeiilglehmhnrfvvyrdlkpanilldeh
ghvrisdlglacdfskkkphasvgthgymapevlqkgvaydssadwfslgcmlfkllrgh
spfrqhktkdkheidrmtltmavelpdsfspelrsllegllqrdvnrrlgclgrgaqevk
espffrsldwqmvflqkyppplipprgtkgiklldsdqelyrnfpltiserwqqevaetv
fdtinaetdrlearkktdyalgkdcimhgymskmgntqwqrryfylfpnrlewrgegeap
qslltmeeiqsveetqikerkclllkirggkqfvlqcdsdpelvqwkkelrdayreaqq