PDB entry 1yfh

View 1yfh on RCSB PDB site
Description: wt Human O6-Alkylguanine-DNA Alkyltransferase Bound To DNA Containing an Alkylated Cytosine
Class: transferase/DNA
Keywords: protein-DNA complex, TRANSFERASE/DNA COMPLEX
Deposited on 2004-12-31, released 2005-12-13
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 3.01 Å
R-factor: 0.246
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: methylated-DNA--protein-cysteine methyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: MGMT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d1yfha1, d1yfha2
  • Chain 'B':
    Compound: methylated-DNA--protein-cysteine methyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: MGMT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d1yfhb1, d1yfhb2
  • Chain 'C':
    Compound: methylated-DNA--protein-cysteine methyltransferase
    Species: Homo sapiens [TaxId:9606]
    Gene: MGMT
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.01: d1yfhc1, d1yfhc2
  • Chain 'D':
    Compound: 5'-d(*gp*tp*gp*gp*ap*tp*gp*(xcy)p*gp*tp*gp*tp*ap*gp*gp*t)-3'
    Species: synthetic, synthetic
  • Chain 'E':
    Compound: 5'-d(*cp*cp*tp*ap*cp*ap*cp*ap*cp*ap*tp*cp*cp*ap*cp*a)-3'
    Species: synthetic, synthetic
  • Chain 'F':
    Compound: 5'-d(*gp*tp*gp*gp*ap*tp*gp*(xcy)p*gp*tp*gp*tp*ap*gp*gp*t)-3'
    Species: synthetic, synthetic
  • Chain 'G':
    Compound: 5'-d(*cp*cp*tp*ap*cp*ap*cp*ap*cp*ap*tp*cp*cp*ap*cp*a)-3'
    Species: synthetic, synthetic
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1yfhA (A:)
mdkdcemkrttldsplgklelsgceqglheikllgkgtsaadavevpapaavlggpeplm
qctawlnayfhqpeaieefpvpalhhpvfqqesftrqvlwkllkvvkfgevisyqqlaal
agnpkaaravggamrgnpvpilipchrvvcssgavgnysgglavkewllaheghrlgkp

    Sequence, based on observed residues (ATOM records): (download) 
    >1yfhA (A:)
cemkrttldsplgklelsgceqglheikllgvpapaavlggpeplmqctawlnayfhqpe
aieefpvpalhhpvfqqesftrqvlwkllkvvkfgevisyqqlaalagnpkaaravggam
rgnpvpilipchrvvcssgavgnysgglavkewllaheghrlgkp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1yfhB (B:)
mdkdcemkrttldsplgklelsgceqglheikllgkgtsaadavevpapaavlggpeplm
qctawlnayfhqpeaieefpvpalhhpvfqqesftrqvlwkllkvvkfgevisyqqlaal
agnpkaaravggamrgnpvpilipchrvvcssgavgnysgglavkewllaheghrlgkp

    Sequence, based on observed residues (ATOM records): (download) 
    >1yfhB (B:)
cemkrttldsplgklelsgceqglheikllgvpapaavlggpeplmqctawlnayfhqpe
aieefpvpalhhpvfqqesftrqvlwkllkvvkfgevisyqqlaalagnpkaaravggam
rgnpvpilipchrvvcssgavgnysgglavkewllaheghr

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1yfhC (C:)
mdkdcemkrttldsplgklelsgceqglheikllgkgtsaadavevpapaavlggpeplm
qctawlnayfhqpeaieefpvpalhhpvfqqesftrqvlwkllkvvkfgevisyqqlaal
agnpkaaravggamrgnpvpilipchrvvcssgavgnysgglavkewllaheghrlgkp

    Sequence, based on observed residues (ATOM records): (download) 
    >1yfhC (C:)
cemkrttldsplgklelsgceqglheikllggpeplmqctawlnayfhqpeaieefpvpa
lhhpvfqqesftrqvlwkllkvvkfgevisyqqlaalagnpkaaravggamrgnpvpili
pchrvvcssgavglavkewllaheghrlg

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.