PDB entry 1y91

View 1y91 on RCSB PDB site
Description: Crystal structure of human CDK2 complexed with a pyrazolo[1,5-a]pyrimidine inhibitor
Class: transferase
Keywords: Serine/Threonine protein kinase, CDK2, ATP-binding, Cell cycle, mitosis, phosphorylation, pyrazolopyrimidine inhibitor
Deposited on 2004-12-14, released 2005-02-08
The last revision prior to the SCOP 1.75 freeze date was dated 2005-02-08, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: 0.201
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: HOMO SAPIENS
    Gene: CDK2
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1y91a1
  • Heterogens: CT9, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1y91A (A:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

    Sequence, based on observed residues (ATOM records): (download) 
    >1y91A (A:)
menfqkvekigegtygvvykarnkltgevvalkkirlpstaireisllkelnhpnivkll
dvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrd
lkpqnllintegaikladfglarafgythevvtlwyrapeillgckyystavdiwslgci
faemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvv
ppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl