PDB entry 1y91

View 1y91 on RCSB PDB site
Description: Crystal structure of human CDK2 complexed with a pyrazolo[1,5-a]pyrimidine inhibitor
Class: transferase
Keywords: Serine/Threonine protein kinase, CDK2, ATP-binding, Cell cycle, mitosis, phosphorylation, pyrazolopyrimidine inhibitor, TRANSFERASE
Deposited on 2004-12-14, released 2005-02-08
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: 0.201
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CDK2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1y91a_
  • Heterogens: CT9, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1y91A (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
    pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
    hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
    stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
    pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
    

    Sequence, based on observed residues (ATOM records): (download)
    >1y91A (A:)
    menfqkvekigegtygvvykarnkltgevvalkkirlpstaireisllkelnhpnivkll
    dvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrd
    lkpqnllintegaikladfglarafgythevvtlwyrapeillgckyystavdiwslgci
    faemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqdfskvv
    ppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl