PDB entry 1y8x

View 1y8x on RCSB PDB site
Description: Structural basis for recruitment of Ubc12 by an E2-binding domain in NEDD8's E1
Class: ligase
Keywords: Ubiquitin-conjugating enzyme E2 M , LIGASE
Deposited on 2004-12-13, released 2005-02-08
The last revision prior to the SCOP 1.73 freeze date was dated 2005-02-08, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.242
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Ubiquitin-conjugating enzyme E2 M
  Species: HOMO SAPIENS
  Gene: UBE2M, UBC12
  Database cross-references and differences (RAF-indexed):
  • Uniprot P61081 (3-159)
    • cloning artifact (0-2)
    • modified residue (74)
    • modified residue (144)
  Domains in SCOP 1.73: d1y8xa1
• Chain 'B':
  Compound: ubiquitin-activating enzyme E1C
  Species: HOMO SAPIENS
  Gene: UBE1C, UBA3
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q8TBC4
    • modified residue (31)
    • engineered (49)
• Heterogens: HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >1y8xA (A:)
  gsmasaaqlriqkdinelnlpktcdisfsdpddllnfklvicpdegfyksgkfvfsfkvg
  qgyphdppkvkcetmvyhpnidlegnvclnilredwkpvltinsiiyglqylflepnped
  plnkeaaevlqnnrrlfeqnvqrsmrggyigstyferclk
  

  
  
• Chain 'B':
  No sequence available.