PDB entry 1xz4

View 1xz4 on RCSB PDB site
Description: Intersubunit Interactions Associated with Tyr42alpha Stabilize the Quaternary-T Tetramer but are not Major Quaternary Constraints in Deoxyhemoglobin: alphaY42A deoxyhemoglobin no-salt
Class: transport protein
Keywords: hemoglobin mutant, globin
Deposited on 2004-11-11, released 2004-11-30
The last revision prior to the SCOP 1.75 freeze date was dated 2005-03-22, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.187
AEROSPACI score: 0.54 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hemoglobin alpha chain
    Species: HOMO SAPIENS
    Gene: HBA1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01922 (0-140)
      • engineered (0)
      • engineered (41)
    Domains in SCOP 1.75: d1xz4a_
  • Chain 'B':
    Compound: hemoglobin beta chain
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1xz4b_
  • Chain 'C':
    Compound: hemoglobin alpha chain
    Species: HOMO SAPIENS
    Gene: HBA1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01922 (0-140)
      • engineered (0)
      • engineered (41)
    Domains in SCOP 1.75: d1xz4c_
  • Chain 'D':
    Compound: hemoglobin beta chain
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1xz4d_
  • Heterogens: HEM, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1xz4A (A:)
    mlspadktnvkaawgkvgahageygaealermflsfpttktafphfdlshgsaqvkghgk
    kvadaltnavahvddmpnalsalsdlhahklrvdpvnfkllshcllvtlaahlpaeftpa
    vhasldkflasvstvltskyr
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1xz4B (B:)
    vhltpeeksavtalwgkvnvdevggealgrllvvypwtqrffesfgdlstpdavmgnpkv
    kahgkkvlgafsdglahldnlkgtfatlselhcdklhvdpenfrllgnvlvcvlahhfgk
    eftppvqaayqkvvagvanalahkyh
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1xz4C (C:)
    mlspadktnvkaawgkvgahageygaealermflsfpttktafphfdlshgsaqvkghgk
    kvadaltnavahvddmpnalsalsdlhahklrvdpvnfkllshcllvtlaahlpaeftpa
    vhasldkflasvstvltskyr
    

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1xz4D (D:)
    vhltpeeksavtalwgkvnvdevggealgrllvvypwtqrffesfgdlstpdavmgnpkv
    kahgkkvlgafsdglahldnlkgtfatlselhcdklhvdpenfrllgnvlvcvlahhfgk
    eftppvqaayqkvvagvanalahkyh