PDB entry 1xsp

View 1xsp on RCSB PDB site
Description: Crystal Structure of human DNA polymerase lambda in complex with nicked DNA and pyrophosphate
Class: transferase/DNA
Keywords: DNA POLYMERASE LAMBDA, Protein-DNA complex, Helix-hairpin-helix
Deposited on 2004-10-19, released 2005-01-18
The last revision prior to the SCOP 1.75 freeze date was dated 2005-01-18, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.206
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: DNA polymerase lambda
    Species: HOMO SAPIENS
    Gene: POLL
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9UGP5 (Start-334)
      • engineered (302)
    Domains in SCOP 1.75: d1xspa1, d1xspa2, d1xspa3
  • Chain 'D':
    Compound: 5'-d(p*gp*cp*cp*g)-3'
    Species: synthetic, synthetic
  • Chain 'P':
    Compound: 5'-d(*cp*ap*gp*tp*ap*cp*g)-3'
    Species: synthetic, synthetic
  • Chain 'T':
    Compound: 5'-d(*cp*gp*gp*cp*cp*gp*tp*ap*cp*tp*g)-3'
    Species: synthetic, synthetic
  • Heterogens: NA, PPV, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1xspA (A:)
maqpssqkatnhnlhiteklevlakaysvqgdkwralgyakainalksfhkpvtsyqeac
sipgigkrmaekiieilesghlrkldhisesvpvlelfsniwgagtktaqmwyqqgfrsl
edirsqaslttqqaiglkhysdflermpreeateieqtvqkaaqafnsgllcvacgsyrr
gkatcgdvdvlithpdgrshrgifsrlldslrqegfltddlvsqeengqqqkylgvcrlp
gpgrrhrrldiivvpysefacallyftgsahfnrsmralaktkgmslsehalstavvrnt
hgakvgpgrvlptptekdvfrllglpyrepaerdw

    Sequence, based on observed residues (ATOM records): (download) 
    >1xspA (A:)
atnhnlhiteklevlakaysvqgdkwralgyakainalksfhkpvtsyqeacsipgigkr
maekiieilesghlrkldhisesvpvlelfsniwgagtktaqmwyqqgfrsledirsqas
lttqqaiglkhysdflermpreeateieqtvqkaaqafnsgllcvacgsyrrgkatcgdv
dvlithpdgrshrgifsrlldslrqegfltddlvsqeengqqqkylgvcrlpgpgrrhrr
ldiivvpysefacallyftgsahfnrsmralaktkgmslsehalstavvrnthgakvgpg
rvlptptekdvfrllglpyrepaerdw

  • Chain 'D':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'T':
    No sequence available.