PDB entry 1xka

View 1xka on RCSB PDB site
Description: factor xa complexed with a synthetic inhibitor fx-2212a,(2s)-(3'-amidino-3-biphenylyl)-5-(4-pyridylamino)pentanoic acid
Class: blood coagulation factor
Keywords: blood coagulation factor, serine proteinase, epidermal growth factor like domain
Deposited on 1998-03-19, released 1999-03-23
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-06-20, with a file datestamp of 2012-06-15.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.287
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'C':
    Compound: blood coagulation factor xa
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1xkac_
  • Chain 'L':
    Compound: blood coagulation factor xa
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00742 (Start-94)
      • modified residue (18)
    Domains in SCOPe 2.06: d1xkal1, d1xkal2
  • Heterogens: CA, 4PP, HOH

PDB Chain Sequences:

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1xkaC (C:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktr

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >1xkaL (L:)
kdgdqcetspcqnqgkckdglgeytctclegfegkncelftrklcsldngdcdqfcheeq
nsvvcscargytladngkaciptgpypcgkqtler

    Sequence, based on observed residues (ATOM records): (download) 
    >1xkaL (L:)
qcetspcqnqgkckdglgeytctclegfegkncelftrklcsldngdcdqfcheeqnsvv
cscargytladngkaciptgpypcgkqtler