PDB entry 1xha
View 1xha on RCSB PDB site
Description: Crystal Structures of Protein Kinase B Selective Inhibitors in Complex with Protein Kinase A and Mutants
Class: transferase/transferase inhibitor
Keywords: PKA, kinase-inhibitor-complex, serine/threonine-protein kinase, balanol derivative, TRANSFERASE/TRANSFERASE INHIBITOR COMPLEX
Deposited on
2004-09-17, released
2005-09-17
The last revision prior to the SCOPe 2.08 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 2.46 Å
R-factor: 0.223
AEROSPACI score: 0.3
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: cAMP-dependent protein kinase, alpha-catalytic subunit
Species: Bos taurus [TaxId:9913]
Gene: PRKACA
Database cross-references and differences (RAF-indexed):
- Uniprot P00517 (0-349)
- engineered (83)
- engineered (122)
- engineered (172)
- engineered (186)
- modified residue (196)
- modified residue (337)
Domains in SCOPe 2.08: d1xhaa_ - Chain 'B':
Compound: cAMP-dependent protein kinase inhibitor, alpha form
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Heterogens: R68, HOH