PDB entry 1x6v

View 1x6v on RCSB PDB site
Description: The crystal structure of human 3'-phosphoadenosine-5'-phosphosulfate synthetase 1
Class: transferase
Keywords: transferase, ATP sulfurylase, APS kinase, PAPS, phosphoadenosine phosphosulfate
Deposited on 2004-08-12, released 2005-03-22
The last revision prior to the SCOPe 2.01 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.75 Å
R-factor: 0.168
AEROSPACI score: 0.55 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthethase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PAPSS1, PAPSS, ATPSK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O43252 (Start-623)
      • conflict (415)
      • expression tag (627-629)
    Domains in SCOPe 2.01: d1x6va1, d1x6va2, d1x6va3
  • Chain 'B':
    Compound: Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthethase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: PAPSS1, PAPSS, ATPSK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O43252
      • conflict (415)
    Domains in SCOPe 2.01: d1x6vb1, d1x6vb2, d1x6vb3
  • Heterogens: CL, ADP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1x6vA (A:)
meipgslckkvklsnnaqnwgmqratnvtyqahhvsrnkrgqvvgtrggfrgctvwltgl
sgagkttvsmaleeylvchgipcytldgdnirqglnknlgfspedreenvrriaevaklf
adaglvcitsfispytqdrnnarqihegaslpffevfvdaplhvceqrdvkglykkarag
eikgftgidseyekpeapelvlktdscdvndcvqqvvellqerdivpvdasyevkelyvp
enklhlaktdaetlpalkinkvdmqwvqvlaegwatplngfmrereylqclhfdclldgg
vinlsvpivltathedkerldgctafalmyegrrvailrnpeffehrkeercarqwgttc
knhpyikmvmeqgdwliggdlqvldrvywndgldqyrltptelkqkfkdmnadavsafql
rnpvhnghallmqdthkqllergyrrpvlllhplggwtkdddvplmwrmkqhaavleegv
lnpettvvaifpspmmyagptevqwhcrarmvaganfyivgrdpagmphpetgkdlyeps
hgakvltmapglitleivpfrvaaynkkkkrmdyydsehhedfefisgtrmrklaregqk
ppegfmapkawtvlteyykslekahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1x6vA (A:)
hvsrnkrgqvvgtrggfrgctvwltglsgagkttvsmaleeylvchgipcytldgdnirq
glnknlgfspedreenvrriaevaklfadaglvcitsfispytqdrnnarqihegaslpf
fevfvdaeyekpeapelvlktdscdvndcvqqvvellqerdivpvdasyevkelyvpenk
lhlaktdaetlpalkinkvdmqwvqvlaegwatplngfmrereylqclhfdclldggvin
lsvpivltathedkerldgctafalmyegrrvailrnpeffehrkeercarqwgttcknh
pyikmvmeqgdwliggdlqvldrvywndgldqyrltptelkqkfkdmnadavsafqlrnp
vhnghallmqdthkqllergyrrpvlllhplggwtkdddvplmwrmkqhaavleegvlnp
ettvvaifpspmmyagptevqwhcrarmvaganfyivgrdpagmphpetgkdlyepshga
kvltmapglitleivpfrvaaynkkkkrmdyydsehhedfefisgtrmrklaregqkppe
gfmapkawtvlteyykslekahhh

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1x6vB (B:)
meipgslckkvklsnnaqnwgmqratnvtyqahhvsrnkrgqvvgtrggfrgctvwltgl
sgagkttvsmaleeylvchgipcytldgdnirqglnknlgfspedreenvrriaevaklf
adaglvcitsfispytqdrnnarqihegaslpffevfvdaplhvceqrdvkglykkarag
eikgftgidseyekpeapelvlktdscdvndcvqqvvellqerdivpvdasyevkelyvp
enklhlaktdaetlpalkinkvdmqwvqvlaegwatplngfmrereylqclhfdclldgg
vinlsvpivltathedkerldgctafalmyegrrvailrnpeffehrkeercarqwgttc
knhpyikmvmeqgdwliggdlqvldrvywndgldqyrltptelkqkfkdmnadavsafql
rnpvhnghallmqdthkqllergyrrpvlllhplggwtkdddvplmwrmkqhaavleegv
lnpettvvaifpspmmyagptevqwhcrarmvaganfyivgrdpagmphpetgkdlyeps
hgakvltmapglitleivpfrvaaynkkkkrmdyydsehhedfefisgtrmrklaregqk
ppegfmapkawtvlteyykslekahhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1x6vB (B:)
hvsrnkrgqvvgtrggfrgctvwltglsgagkttvsmaleeylvchgipcytldgdnirq
glnknlgfspedreenvrriaevaklfadaglvcitsfispytqdrnnarqihegaslpf
fevfvdaplhvceqrdvkglykkaragftgidseyekpeapelvlktdscdvndcvqqvv
ellqerdivpvdasyevkelyvpenklhlaktdaetlpalkinkvdmqwvqvlaegwatp
lngfmrereylqclhfdclldggvinlsvpivltathedkerldgctafalmyegrrvai
lrnpeffehrkeercarqwgttcknhpyikmvmeqgdwliggdlqvldrvywndgldqyr
ltptelkqkfkdmnadavsafqlrnpvhnghallmqdthkqllergyrrpvlllhplggw
tkdddvplmwrmkqhaavleegvlnpettvvaifpspmmyagptevqwhcrarmvaganf
yivgrdpagmphpetgkdlyepshgakvltmapglitleivpfrvaaynkkkkrmdyyds
ehhedfefisgtrmrklaregqkppegfmapkawtvlteyykslek