PDB entry 1wq1

View 1wq1 on RCSB PDB site
Description: ras-rasgap complex
Class: complex (GTP-binding/gtpase activation)
Keywords: ras, gap, signal transduction, growth regulation, GTP hydrolysis, transition state, complex (GTP-binding/gtpase activation)
Deposited on 1997-07-03, released 1998-07-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.233
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'G':
    Compound: p120gap
    Species: Homo sapiens [TaxId:9606]
    Gene: GENE FRAGMENT OF P120GAP POSI
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1wq1g_
  • Chain 'R':
    Compound: h-ras
    Species: Homo sapiens [TaxId:9606]
    Gene: H-RAS-1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1wq1r_
  • Heterogens: MG, GDP, AF3, HOH

PDB Chain Sequences:

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >1wq1G (G:)
    mekimpeeeysefkelilqkelhvvyalshvcgqdrtllasillriflhekleslllctl
    ndreismedeattlfrattlastlmeqymkatatqfvhhalkdsilkimeskqscelsps
    kleknedvntnlthllnilselvekifmaseilpptlryiygclqksvqhkwptnttmrt
    rvvsgfvflrlicpailnprmfniisdspspiaartlilvaksvqnlanlvefgakepym
    egvnpfiksnkhrmimfldelgnvpelpdttehsrtdlsrdlaalheicvahsdelrtls
    nergaqqhvlkkllaitellqqkqnqytktndvr
    

    Sequence, based on observed residues (ATOM records): (download)
    >1wq1G (G:)
    mpeeeysefkelilqkelhvvyalshvcgqdrtllasillriflhekleslllctlndre
    ismedeattlfrattlastlmeqymkatatqfvhhalkdsilkimeskqscelspsklek
    nedvntnlthllnilselvekifmaseilpptlryiygclqksvqhkwptnttmrtrvvs
    gfvflrlicpailnprmfniisdspspiaartlilvaksvqnlanlvefgakepymegvn
    pfiksnkhrmimfldelgnvpelpdttehsrtdlsrdlaalheicvahsdelrtlsnerg
    aqqhvlkkllaitellqqkq
    

  • Chain 'R':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1wq1R (R:)
    mteyklvvvgaggvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildtag
    qeeysamrdqymrtgegflcvfainntksfedihqyreqikrvkdsddvpmvlvgnkcdl
    aartvesrqaqdlarsygipyietsaktrqgvedafytlvreirqh