PDB entry 1w9u

View 1w9u on RCSB PDB site
Description: Specificity and affnity of natural product cyclopentapeptide inhibitor Argadin against Aspergillus fumigatus chitinase
Class: hydrolase/hydrolase inhibitor
Keywords: chitinase, argadin, cyclopentapeptide inhibitors, chitinase inhibitors, glycosidase, hydrolase-hydrolase inhibitor complex
Deposited on 2004-10-19, released 2004-11-17
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-08-05, with a file datestamp of 2015-07-31.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: chitinase
    Species: Aspergillus fumigatus [TaxId:746128]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1w9ua1, d1w9ua2
  • Chain 'B':
    Compound: chitinase
    Species: Aspergillus fumigatus [TaxId:746128]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1w9ub1, d1w9ub2
  • Chain 'C':
    Compound: argadin
    Species: CLONOSTACHYS, synthetic [TaxId:110564]
    Database cross-references and differences (RAF-indexed):
    • PDB 1W9U (0-4)
  • Chain 'D':
    Compound: argadin
    Species: CLONOSTACHYS, synthetic [TaxId:110564]
    Database cross-references and differences (RAF-indexed):
    • PDB 1W9U (0-4)
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1w9uA (A:)
    mrfatstivkvalllsslcvdaavmwnrdtsstdlearassgyrsvvyfvnwaiygrnhn
    pqdlpverlthvlyafanvrpetgevymtdswadiekhypgdswsdtgnnvygcikqlyl
    lkkqnrnlkvllsiggwtyspnfapaastdagrknfaktavkllqdlgfdgldidweype
    ndqqandfvlllkevrtaldsysaanaggqhflltvaspagpdkikvlhlkdmdqqldfw
    nlmaydyagsfsslsghqanvyndtsnplstpfntqtaldlyraggvpankivlgmplyg
    rsfantdgpgkpyngvgqgswengvwdykalpqagatehvlpdimasysydatnkflisy
    dnpqvanlksgyikslglggamwwdsssdktgsdslittvvnalggtgvfeqsqneldyp
    vsqydnlrngmqt
    

    Sequence, based on observed residues (ATOM records): (download)
    >1w9uA (A:)
    assgyrsvvyfvnwaiygrnhnpqdlpverlthvlyafanvrpetgevymtdswadiekh
    ypgdswsdtgnnvygcikqlyllkkqnrnlkvllsiggwtyspnfapaastdagrknfak
    tavkllqdlgfdgldidweypendqqandfvlllkevrtaldsysaanaggqhflltvas
    pagpdkikvlhlkdmdqqldfwnlmaydyagsfsslsghqanvyndtsnplstpfntqta
    ldlyraggvpankivlgmplygrsfantdgpgkpyngvgqgswengvwdykalpqagate
    hvlpdimasysydatnkflisydnpqvanlksgyikslglggamwwdsssdktgsdslit
    tvvnalggtgvfeqsqneldypvsqydnlrngmqt
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1w9uB (B:)
    mrfatstivkvalllsslcvdaavmwnrdtsstdlearassgyrsvvyfvnwaiygrnhn
    pqdlpverlthvlyafanvrpetgevymtdswadiekhypgdswsdtgnnvygcikqlyl
    lkkqnrnlkvllsiggwtyspnfapaastdagrknfaktavkllqdlgfdgldidweype
    ndqqandfvlllkevrtaldsysaanaggqhflltvaspagpdkikvlhlkdmdqqldfw
    nlmaydyagsfsslsghqanvyndtsnplstpfntqtaldlyraggvpankivlgmplyg
    rsfantdgpgkpyngvgqgswengvwdykalpqagatehvlpdimasysydatnkflisy
    dnpqvanlksgyikslglggamwwdsssdktgsdslittvvnalggtgvfeqsqneldyp
    vsqydnlrngmqt
    

    Sequence, based on observed residues (ATOM records): (download)
    >1w9uB (B:)
    assgyrsvvyfvnwaiygrnhnpqdlpverlthvlyafanvrpetgevymtdswadiekh
    ypgdswsdtgnnvygcikqlyllkkqnrnlkvllsiggwtyspnfapaastdagrknfak
    tavkllqdlgfdgldidweypendqqandfvlllkevrtaldsysaanaggqhflltvas
    pagpdkikvlhlkdmdqqldfwnlmaydyagsfsslsghqanvyndtsnplstpfntqta
    ldlyraggvpankivlgmplygrsfantdgpgkpyngvgqgswengvwdykalpqagate
    hvlpdimasysydatnkflisydnpqvanlksgyikslglggamwwdsssdktgsdslit
    tvvnalggtgvfeqsqneldypvsqydnlrngmqt
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.