PDB entry 1w8c
View 1w8c on RCSB PDB site
Description: co-crystal structure of 6-cyclohexylmethoxy-8-isopropyl-9h-purin-2-ylamine and monomeric cdk2
Class: transferase
Keywords: transferase, protein kinase, cell cycle, phosphorylation, cell division, mitosis, inhibition
Deposited on
2004-09-20, released
2006-08-30
The last revision prior to the SCOPe 2.01 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.199
AEROSPACI score: 0.41
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Cell division protein kinase 2
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- PDB 1W8C
- Uniprot P24941 (0-297)
Domains in SCOPe 2.01: d1w8ca_ - Heterogens: N69, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1w8cA (A:)
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl
Sequence, based on observed residues (ATOM records): (download)
>1w8cA (A:)
menfqkvekigegtygvvykarnkltgevvalkkirvpstaireisllkelnhpnivkll
dvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchshrvlhrd
lkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyystavdiw
slgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsfpkwarqd
fskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl