PDB entry 1w5v

View 1w5v on RCSB PDB site
Description: hiv-1 protease in complex with fluoro substituted diol-based c2-symmetric inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: hydrolase/hydrolase inhibitor, hydrolase, dimer, protein-inhibitor complex
Deposited on 2004-08-10, released 2004-12-01
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.189
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hiv-1 protease
    Species: HUMAN IMMUNODEFICIENCY VIRUS [TaxId:12721]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1w5va_
  • Chain 'B':
    Compound: hiv-1 protease
    Species: HUMAN IMMUNODEFICIENCY VIRUS [TaxId:12721]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1w5vb_
  • Heterogens: BE3, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1w5vA (A:)
    adrqgtvsfnfpqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmigg
    iggfikvrqydqilieicghkaigtvlvgptpvniigrnlltqigctlnf
    

    Sequence, based on observed residues (ATOM records): (download)
    >1w5vA (A:)
    pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
    qilieicghkaigtvlvgptpvniigrnlltqigctlnf
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1w5vB (B:)
    adrqgtvsfnfpqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmigg
    iggfikvrqydqilieicghkaigtvlvgptpvniigrnlltqigctlnf
    

    Sequence, based on observed residues (ATOM records): (download)
    >1w5vB (B:)
    pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
    qilieicghkaigtvlvgptpvniigrnlltqigctlnf