PDB entry 1vu3

View 1vu3 on RCSB PDB site
Description: The 8S snRNP Assembly Intermediate
Class: splicing
Keywords: Complex, Assembly Machinery, SPLICING
Deposited on 2012-05-15, released 2013-02-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-12-10, with a file datestamp of 2014-12-05.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: 0.234
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Small nuclear ribonucleoprotein Sm D1
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPD1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vu3a_
  • Chain 'B':
    Compound: Small nuclear ribonucleoprotein Sm D2
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPD2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vu3b_
  • Chain 'C':
    Compound: Small nuclear ribonucleoprotein E
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPE
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vu3c_
  • Chain 'D':
    Compound: Small nuclear ribonucleoprotein F
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPF, PBSCF
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vu3d_
  • Chain 'E':
    Compound: LD23602p
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: Smn, CG16725, Dmel_CG16725
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: cg10419
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: Gem2, CG10419, Dmel_CG10419
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Icln
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: Dmel_CG4924, icln, icln-RA
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Small nuclear ribonucleoprotein G
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPG, PBSCG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vu3h_
  • Chain 'I':
    Compound: Small nuclear ribonucleoprotein Sm D1
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPD1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vu3i_
  • Chain 'J':
    Compound: Small nuclear ribonucleoprotein Sm D2
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPD2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vu3j_
  • Chain 'K':
    Compound: Small nuclear ribonucleoprotein E
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPE
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vu3k_
  • Chain 'L':
    Compound: Small nuclear ribonucleoprotein F
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPF, PBSCF
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vu3l_
  • Chain 'M':
    Compound: LD23602p
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: Smn, CG16725, Dmel_CG16725
    Database cross-references and differences (RAF-indexed):
  • Chain 'N':
    Compound: cg10419
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: Gem2, CG10419, Dmel_CG10419
    Database cross-references and differences (RAF-indexed):
  • Chain 'O':
    Compound: Icln
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: Dmel_CG4924, icln, icln-RA
    Database cross-references and differences (RAF-indexed):
  • Chain 'P':
    Compound: Small nuclear ribonucleoprotein G
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPG, PBSCG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vu3p_
  • Chain 'Q':
    Compound: Small nuclear ribonucleoprotein Sm D1
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPD1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vu3q_
  • Chain 'R':
    Compound: Small nuclear ribonucleoprotein Sm D2
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPD2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vu3r_
  • Chain 'S':
    Compound: Small nuclear ribonucleoprotein E
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPE
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vu3s_
  • Chain 'T':
    Compound: Small nuclear ribonucleoprotein F
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPF, PBSCF
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vu3t_
  • Chain 'U':
    Compound: LD23602p
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: Smn, CG16725, Dmel_CG16725
    Database cross-references and differences (RAF-indexed):
  • Chain 'V':
    Compound: cg10419
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: Gem2, CG10419, Dmel_CG10419
    Database cross-references and differences (RAF-indexed):
  • Chain 'W':
    Compound: Icln
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: Dmel_CG4924, icln, icln-RA
    Database cross-references and differences (RAF-indexed):
  • Chain 'X':
    Compound: Small nuclear ribonucleoprotein G
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPG, PBSCG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vu3x_
  • Chain 'Y':
    Compound: Small nuclear ribonucleoprotein Sm D1
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPD1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vu3y_
  • Chain 'Z':
    Compound: Small nuclear ribonucleoprotein Sm D2
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPD2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vu3z_
  • Chain 'a':
    Compound: Small nuclear ribonucleoprotein E
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPE
    Database cross-references and differences (RAF-indexed):
  • Chain 'b':
    Compound: Small nuclear ribonucleoprotein F
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPF, PBSCF
    Database cross-references and differences (RAF-indexed):
  • Chain 'c':
    Compound: LD23602p
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: Smn, CG16725, Dmel_CG16725
    Database cross-references and differences (RAF-indexed):
  • Chain 'd':
    Compound: cg10419
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: Gem2, CG10419, Dmel_CG10419
    Database cross-references and differences (RAF-indexed):
  • Chain 'e':
    Compound: Icln
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: Dmel_CG4924, icln, icln-RA
    Database cross-references and differences (RAF-indexed):
  • Chain 'f':
    Compound: Small nuclear ribonucleoprotein G
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPG, PBSCG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vu3f_
  • Chain 'g':
    Compound: Small nuclear ribonucleoprotein Sm D1
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPD1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vu3g_
  • Chain 'h':
    Compound: Small nuclear ribonucleoprotein Sm D2
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPD2
    Database cross-references and differences (RAF-indexed):
  • Chain 'i':
    Compound: Small nuclear ribonucleoprotein E
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPE
    Database cross-references and differences (RAF-indexed):
  • Chain 'j':
    Compound: Small nuclear ribonucleoprotein F
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPF, PBSCF
    Database cross-references and differences (RAF-indexed):
  • Chain 'k':
    Compound: LD23602p
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: Smn, CG16725, Dmel_CG16725
    Database cross-references and differences (RAF-indexed):
  • Chain 'l':
    Compound: cg10419
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: Gem2, CG10419, Dmel_CG10419
    Database cross-references and differences (RAF-indexed):
  • Chain 'm':
    Compound: Icln
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: Dmel_CG4924, icln, icln-RA
    Database cross-references and differences (RAF-indexed):
  • Chain 'n':
    Compound: Small nuclear ribonucleoprotein G
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPG, PBSCG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vu3n_
  • Chain 'o':
    Compound: Small nuclear ribonucleoprotein Sm D1
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPD1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vu3o_
  • Chain 'p':
    Compound: Small nuclear ribonucleoprotein Sm D2
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPD2
    Database cross-references and differences (RAF-indexed):
  • Chain 'q':
    Compound: Small nuclear ribonucleoprotein E
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPE
    Database cross-references and differences (RAF-indexed):
  • Chain 'r':
    Compound: Small nuclear ribonucleoprotein F
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPF, PBSCF
    Database cross-references and differences (RAF-indexed):
  • Chain 's':
    Compound: LD23602p
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: Smn, CG16725, Dmel_CG16725
    Database cross-references and differences (RAF-indexed):
  • Chain 't':
    Compound: cg10419
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: Gem2, CG10419, Dmel_CG10419
    Database cross-references and differences (RAF-indexed):
  • Chain 'u':
    Compound: Icln
    Species: Drosophila melanogaster [TaxId:7227]
    Gene: Dmel_CG4924, icln, icln-RA
    Database cross-references and differences (RAF-indexed):
  • Chain 'v':
    Compound: Small nuclear ribonucleoprotein G
    Species: Homo sapiens [TaxId:9606]
    Gene: SNRPG, PBSCG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vu3v_
  • Heterogens: SO4

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1vu3A (A:)
mklvrflmklshetvtielkngtqvhgtitgvdvsmnthlkavkmtlknrepvqletlsi
rgnniryfilpdslpldtllvdvepkvkskkreavagrgrgrgrgrgrgrgrgrggprr

    Sequence, based on observed residues (ATOM records): (download) 
    >1vu3A (A:)
klvrflmklshetvtielkngtqvhgtitgvdvsmnthlkavkmtlknrepvqletlsir
gnniryfilpdslpldtllvdv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1vu3B (B:)
msllnkpksemtpeelqkreeeefntgplsvltqsvknntqvlincrnnkkllgrvkafd
rhcnmvlenvkemwtevpksgkgkkkskpvnkdryiskmflrgdsvivvlrnpliagk

    Sequence, based on observed residues (ATOM records): (download) 
    >1vu3B (B:)
pksemtpeelqkreeeefntgplsvltqsvknntqvlincrnnkkllgrvkafdrhcnmv
lenvkemwtevpvnkdryiskmflrgdsvivvlrnpliag

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1vu3C (C:)
mayrgqgqkvqkvmvqpinlifrylqnrsriqvwlyeqvnmriegciigfdeymnlvldd
aeeihsktksrkqlgrimlkgdnitllqsvsn

    Sequence, based on observed residues (ATOM records): (download) 
    >1vu3C (C:)
mvqpinlifrylqnrsriqvwlyeqvnmriegciigfdeymnlvlddaeeihsktksrkq
lgrimlkgdnitllqsv

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1vu3D (D:)
mslplnpkpflngltgkpvmvklkwgmeykgylvsvdgymnmqlanteeyidgalsghlg
evlircnnvlyirgveeeeedgemre

    Sequence, based on observed residues (ATOM records): (download) 
    >1vu3D (D:)
npkpflngltgkpvmvklkwgmeykgylvsvdgymnmqlanteeyidgalsghlgevlir
cnnvlyirgve

  • Chain 'E':
    No sequence available.

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >1vu3H (H:)
mskahppelkkfmdkklslklnggrhvqgilrgfdpfmnlvidecvematsgqqnnigmv
virgnsiimlealerv

    Sequence, based on observed residues (ATOM records): (download) 
    >1vu3H (H:)
hppelkkfmdkklslklnggrhvqgilrgfdpfmnlvidecvematsgqqnnigmvvirg
nsiimleale

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >1vu3I (I:)
mklvrflmklshetvtielkngtqvhgtitgvdvsmnthlkavkmtlknrepvqletlsi
rgnniryfilpdslpldtllvdvepkvkskkreavagrgrgrgrgrgrgrgrgrggprr

    Sequence, based on observed residues (ATOM records): (download) 
    >1vu3I (I:)
klvrflmklshetvtielkngtqvhgtitgvdvsmnthlkavkmtlknrepvqletlsir
gnniryfilpdslpldtllvdv

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >1vu3J (J:)
msllnkpksemtpeelqkreeeefntgplsvltqsvknntqvlincrnnkkllgrvkafd
rhcnmvlenvkemwtevpksgkgkkkskpvnkdryiskmflrgdsvivvlrnpliagk

    Sequence, based on observed residues (ATOM records): (download) 
    >1vu3J (J:)
pksemtpeelqkreeeefntgplsvltqsvknntqvlincrnnkkllgrvkafdrhcnmv
lenvkemwtevpvnkdryiskmflrgdsvivvlrnpliag

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >1vu3K (K:)
mayrgqgqkvqkvmvqpinlifrylqnrsriqvwlyeqvnmriegciigfdeymnlvldd
aeeihsktksrkqlgrimlkgdnitllqsvsn

    Sequence, based on observed residues (ATOM records): (download) 
    >1vu3K (K:)
mvqpinlifrylqnrsriqvwlyeqvnmriegciigfdeymnlvlddaeeihsktksrkq
lgrimlkgdnitllqsv

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >1vu3L (L:)
mslplnpkpflngltgkpvmvklkwgmeykgylvsvdgymnmqlanteeyidgalsghlg
evlircnnvlyirgveeeeedgemre

    Sequence, based on observed residues (ATOM records): (download) 
    >1vu3L (L:)
npkpflngltgkpvmvklkwgmeykgylvsvdgymnmqlanteeyidgalsghlgevlir
cnnvlyirgve

  • Chain 'M':
    No sequence available.

  • Chain 'N':
    No sequence available.

  • Chain 'O':
    No sequence available.

  • Chain 'P':
    Sequence, based on SEQRES records: (download) 
    >1vu3P (P:)
mskahppelkkfmdkklslklnggrhvqgilrgfdpfmnlvidecvematsgqqnnigmv
virgnsiimlealerv

    Sequence, based on observed residues (ATOM records): (download) 
    >1vu3P (P:)
hppelkkfmdkklslklnggrhvqgilrgfdpfmnlvidecvematsgqqnnigmvvirg
nsiimleale

  • Chain 'Q':
    Sequence, based on SEQRES records: (download) 
    >1vu3Q (Q:)
mklvrflmklshetvtielkngtqvhgtitgvdvsmnthlkavkmtlknrepvqletlsi
rgnniryfilpdslpldtllvdvepkvkskkreavagrgrgrgrgrgrgrgrgrggprr

    Sequence, based on observed residues (ATOM records): (download) 
    >1vu3Q (Q:)
klvrflmklshetvtielkngtqvhgtitgvdvsmnthlkavkmtlknrepvqletlsir
gnniryfilpdslpldtllvdv

  • Chain 'R':
    Sequence, based on SEQRES records: (download) 
    >1vu3R (R:)
msllnkpksemtpeelqkreeeefntgplsvltqsvknntqvlincrnnkkllgrvkafd
rhcnmvlenvkemwtevpksgkgkkkskpvnkdryiskmflrgdsvivvlrnpliagk

    Sequence, based on observed residues (ATOM records): (download) 
    >1vu3R (R:)
pksemtpeelqkreeeefntgplsvltqsvknntqvlincrnnkkllgrvkafdrhcnmv
lenvkemwtevpvnkdryiskmflrgdsvivvlrnpliag

  • Chain 'S':
    Sequence, based on SEQRES records: (download) 
    >1vu3S (S:)
mayrgqgqkvqkvmvqpinlifrylqnrsriqvwlyeqvnmriegciigfdeymnlvldd
aeeihsktksrkqlgrimlkgdnitllqsvsn

    Sequence, based on observed residues (ATOM records): (download) 
    >1vu3S (S:)
mvqpinlifrylqnrsriqvwlyeqvnmriegciigfdeymnlvlddaeeihsktksrkq
lgrimlkgdnitllqsv

  • Chain 'T':
    Sequence, based on SEQRES records: (download) 
    >1vu3T (T:)
mslplnpkpflngltgkpvmvklkwgmeykgylvsvdgymnmqlanteeyidgalsghlg
evlircnnvlyirgveeeeedgemre

    Sequence, based on observed residues (ATOM records): (download) 
    >1vu3T (T:)
npkpflngltgkpvmvklkwgmeykgylvsvdgymnmqlanteeyidgalsghlgevlir
cnnvlyirgve

  • Chain 'U':
    No sequence available.

  • Chain 'V':
    No sequence available.

  • Chain 'W':
    No sequence available.

  • Chain 'X':
    Sequence, based on SEQRES records: (download) 
    >1vu3X (X:)
mskahppelkkfmdkklslklnggrhvqgilrgfdpfmnlvidecvematsgqqnnigmv
virgnsiimlealerv

    Sequence, based on observed residues (ATOM records): (download) 
    >1vu3X (X:)
hppelkkfmdkklslklnggrhvqgilrgfdpfmnlvidecvematsgqqnnigmvvirg
nsiimleale

  • Chain 'Y':
    Sequence, based on SEQRES records: (download) 
    >1vu3Y (Y:)
mklvrflmklshetvtielkngtqvhgtitgvdvsmnthlkavkmtlknrepvqletlsi
rgnniryfilpdslpldtllvdvepkvkskkreavagrgrgrgrgrgrgrgrgrggprr

    Sequence, based on observed residues (ATOM records): (download) 
    >1vu3Y (Y:)
klvrflmklshetvtielkngtqvhgtitgvdvsmnthlkavkmtlknrepvqletlsir
gnniryfilpdslpldtllvdv

  • Chain 'Z':
    Sequence, based on SEQRES records: (download) 
    >1vu3Z (Z:)
msllnkpksemtpeelqkreeeefntgplsvltqsvknntqvlincrnnkkllgrvkafd
rhcnmvlenvkemwtevpksgkgkkkskpvnkdryiskmflrgdsvivvlrnpliagk

    Sequence, based on observed residues (ATOM records): (download) 
    >1vu3Z (Z:)
pksemtpeelqkreeeefntgplsvltqsvknntqvlincrnnkkllgrvkafdrhcnmv
lenvkemwtevpvnkdryiskmflrgdsvivvlrnpliag

  • Chain 'a':
    No sequence available.

  • Chain 'b':
    No sequence available.

  • Chain 'c':
    No sequence available.

  • Chain 'd':
    No sequence available.

  • Chain 'e':
    No sequence available.

  • Chain 'f':
    Sequence, based on SEQRES records: (download) 
    >1vu3f (f:)
mskahppelkkfmdkklslklnggrhvqgilrgfdpfmnlvidecvematsgqqnnigmv
virgnsiimlealerv

    Sequence, based on observed residues (ATOM records): (download) 
    >1vu3f (f:)
hppelkkfmdkklslklnggrhvqgilrgfdpfmnlvidecvematsgqqnnigmvvirg
nsiimleale

  • Chain 'g':
    Sequence, based on SEQRES records: (download) 
    >1vu3g (g:)
mklvrflmklshetvtielkngtqvhgtitgvdvsmnthlkavkmtlknrepvqletlsi
rgnniryfilpdslpldtllvdvepkvkskkreavagrgrgrgrgrgrgrgrgrggprr

    Sequence, based on observed residues (ATOM records): (download) 
    >1vu3g (g:)
klvrflmklshetvtielkngtqvhgtitgvdvsmnthlkavkmtlknrepvqletlsir
gnniryfilpdslpldtllvdv

  • Chain 'h':
    No sequence available.

  • Chain 'i':
    No sequence available.

  • Chain 'j':
    No sequence available.

  • Chain 'k':
    No sequence available.

  • Chain 'l':
    No sequence available.

  • Chain 'm':
    No sequence available.

  • Chain 'n':
    Sequence, based on SEQRES records: (download) 
    >1vu3n (n:)
mskahppelkkfmdkklslklnggrhvqgilrgfdpfmnlvidecvematsgqqnnigmv
virgnsiimlealerv

    Sequence, based on observed residues (ATOM records): (download) 
    >1vu3n (n:)
hppelkkfmdkklslklnggrhvqgilrgfdpfmnlvidecvematsgqqnnigmvvirg
nsiimleale

  • Chain 'o':
    Sequence, based on SEQRES records: (download) 
    >1vu3o (o:)
mklvrflmklshetvtielkngtqvhgtitgvdvsmnthlkavkmtlknrepvqletlsi
rgnniryfilpdslpldtllvdvepkvkskkreavagrgrgrgrgrgrgrgrgrggprr

    Sequence, based on observed residues (ATOM records): (download) 
    >1vu3o (o:)
klvrflmklshetvtielkngtqvhgtitgvdvsmnthlkavkmtlknrepvqletlsir
gnniryfilpdslpldtllvdv

  • Chain 'p':
    No sequence available.

  • Chain 'q':
    No sequence available.

  • Chain 'r':
    No sequence available.

  • Chain 's':
    No sequence available.

  • Chain 't':
    No sequence available.

  • Chain 'u':
    No sequence available.

  • Chain 'v':
    Sequence, based on SEQRES records: (download) 
    >1vu3v (v:)
mskahppelkkfmdkklslklnggrhvqgilrgfdpfmnlvidecvematsgqqnnigmv
virgnsiimlealerv

    Sequence, based on observed residues (ATOM records): (download) 
    >1vu3v (v:)
hppelkkfmdkklslklnggrhvqgilrgfdpfmnlvidecvematsgqqnnigmvvirg
nsiimleale