PDB entry 1vpp

View 1vpp on RCSB PDB site
Description: complex between vegf and a receptor blocking peptide
Class: growth factor/growth factor inhibitor
Keywords: cystine knot, angiogenesis, vasculogenesis, receptor blocking peptide
Deposited on 1998-10-09, released 1999-02-23
The last revision prior to the SCOP 1.75 freeze date was dated 1999-12-29, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.19
AEROSPACI score: 0.57 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'V':
    Compound: protein (vascular endothelial growth factor)
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1vppv_
  • Chain 'W':
    Compound: protein (vascular endothelial growth factor)
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1vppw_
  • Chain 'X':
    Compound: protein (peptide v108)
    Species: synthetic, synthetic
  • Chain 'Y':
    Compound: protein (peptide v108)
    Species: synthetic, synthetic
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'V':
    Sequence, based on SEQRES records: (download)
    >1vppV (V:)
    gqnhhevvkfmdvyqrsychpietlvdifqeypdeieyifkpscvplmrcggccndegle
    cvpteesnitmqimrikphqgqhigemsflqhnkcecrpkkd
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vppV (V:)
    evvkfmdvyqrsychpietlvdifqeypdeieyifkpscvplmrcggccndeglecvpte
    esnitmqimrikphqgqhigemsflqhnkcecrpkk
    

  • Chain 'W':
    Sequence, based on SEQRES records: (download)
    >1vppW (W:)
    gqnhhevvkfmdvyqrsychpietlvdifqeypdeieyifkpscvplmrcggccndegle
    cvpteesnitmqimrikphqgqhigemsflqhnkcecrpkkd
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vppW (W:)
    evvkfmdvyqrsychpietlvdifieyifkpscvplmrcggccndeglecvpteesnitm
    qimrikphqgqhigemsflqhnkcecrpkk
    

  • Chain 'X':
    No sequence available.

  • Chain 'Y':
    No sequence available.