PDB entry 1uvr

View 1uvr on RCSB PDB site
Description: structure of human pdk1 kinase domain in complex with bim-8
Class: transferase
Keywords: protein kinase, pkb, pdk1, inhibitor, ly333531, bisindolyl maleimide, bim-8, diabetes, cancer, transferase
Deposited on 2004-01-22, released 2004-03-04
The last revision prior to the SCOP 1.73 freeze date was dated 2004-03-18, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.81 Å
R-factor: 0.17642
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-phosphoinositide dependent protein kinase-1
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1uvra_
  • Heterogens: SO4, BI8, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1uvrA (A:)
ppqprkkrpedfkfgkilgegsfstvvlarelatsreyaikilekrhiikenkvpyvtre
rdvmsrldhpffvklyftfqddeklyfglsyakngellkyirkigsfdetctrfytaeiv
saleylhgkgiihrdlkpenillnedmhiqitdfgtakvlspeskqaransfvgtaqyvs
pellteksackssdlwalgciiyqlvaglppfragneylifqkiikleydfpekffpkar
dlvekllvldatkrlgceemegygplkahpffesvtwenlhqqtppklt

    Sequence, based on observed residues (ATOM records): (download) 
    >1uvrA (A:)
ppqprkkrpedfkfgkilgegsfstvvlarelatsreyaikilekrhiikenkvpyvtre
rdvmsrldhpffvklyftfqddeklyfglsyakngellkyirkigsfdetctrfytaeiv
saleylhgkgiihrdlkpenillnedmhiqitdfgtakvlsparansfvgtaqyvspell
teksackssdlwalgciiyqlvaglppfragneylifqkiikleydfpekffpkardlve
kllvldatkrlgceemegygplkahpffesvtwenlhqqtppklt