PDB entry 1uvq

View 1uvq on RCSB PDB site
Description: Crystal structure of HLA-DQ0602 in complex with a hypocretin peptide
Class: immune system
Keywords: immunology, MHC class II, diabetes, narcolepsy, autoimmune disease, structural proteomics in europe, spine, structural genomics, immune system
Deposited on 2004-01-22, released 2004-02-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla class II histocompatibility antigen
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1uvqa1, d1uvqa2
  • Chain 'B':
    Compound: hla class II histocompatibility antigen
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03992 (0-End)
    • PDB 1UVQ
    Domains in SCOPe 2.08: d1uvqb1, d1uvqb2
  • Chain 'C':
    Compound: orexin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 1UVQ (17-End)
    • Uniprot O43612 (5-16)
  • Heterogens: GLY, NAG, ZN, ACY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1uvqA (A:)
edivadhvascgvnlyqfygpsgqythefdgdeqfyvdlerketawrwpefskfggfdpq
galrnmavakhnlnimikrynstaatnevpevtvfskspvtlgqpntliclvdnifppvv
nitwlsngqsvtegvsetsflsksdhsffkisyltflpsadeiydckvehwgldqpllkh
wepeipapmseltetvd

    Sequence, based on observed residues (ATOM records): (download) 
    >1uvqA (A:)
divadhvascgvnlyqfygpsgqythefdgdeqfyvdlerketawrwpefskfggfdpqg
alrnmavakhnlnimikrynstaatnevpevtvfskspvtlgqpntliclvdnifppvvn
itwlsngqsvtegvsetsflsksdhsffkisyltflpsadeiydckvehwgldqpllkhw
ep

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1uvqB (B:)
spedfvfqfkgmcyftngtervrlvtryiynreeyarfdsdvgvyravtpqgrpdaeywn
sqkevlegtraeldtvcrhnyevafrgilqrrveptvtispsrtealnhhnllvcsvtdf
ypgqikvrwfrndqeetagvvstplirngdwtfqilvmlemtpqrgdvytchvehpslqs
pitvewraqsesaqskvd

    Sequence, based on observed residues (ATOM records): (download) 
    >1uvqB (B:)
spedfvfqfkgmcyftngtervrlvtryiynreeyarfdsdvgvyravtpqgrpdaeywn
sqkevlegtraeldtvcrhnyevafrgilqrrveptvtispsnllvcsvtdfypgqikvr
wfrndqeetagvvstplirngdwtfqilvmlemtpqrgdvytchvehpslqspitvewra
q

  • Chain 'C':
    No sequence available.