PDB entry 1upw

View 1upw on RCSB PDB site
Description: crystal structure of the human liver x receptor beta ligand binding domain in complex with a synthetic agonist
Class: receptor
Keywords: nuclear hormone receptor, ligand binding domain, liver x receptor, crystal structure, transcription factor
Deposited on 2003-10-13, released 2004-10-20
The last revision prior to the SCOP 1.73 freeze date was dated 2004-10-20, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.2499
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: oxysterols receptor lxr-beta
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1upwa_
  • Heterogens: 444

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1upwA (A:)
    gshmsqgsgegegvqltaaqelmiqqlvaaqlqcnkrsfsdqpkvtpwplgadpqsrdar
    qqrfahftelaiisvqeivdfakqvpgflqlgredqiallkastieimlletarrynhet
    ecitflkdftyskddfhraglqvefinpifefsramrrlglddaeyalliainifsadrp
    nvqepgrvealqqpyveallsytrikrpqdqlrfprmlmklvslrtlssvhseqvfalrl
    qdkklppllseiwdvhe
    

    Sequence, based on observed residues (ATOM records): (download)
    >1upwA (A:)
    qltaaqelmiqqlvaaqlqvtpwplgadpqsrdarqqrfahftelaiisvqeivdfakqv
    pgflqlgredqiallkastieimlletarrynhetecitflkdftyskddfhraglqvef
    inpifefsramrrlglddaeyalliainifsadrpnvqepgrvealqqpyveallsytri
    krpqdqlrfprmlmklvslrtlssvhseqvfalrlqdkklppllseiwdvhe