PDB entry 1ukh

View 1ukh on RCSB PDB site
Description: Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125
Class: transferase
Keywords: TRANSFERASE, Phosphorylation
Deposited on 2003-08-23, released 2004-08-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.226
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: mitogen-activated protein kinase 8 isoform 4
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1ukha_
  • Chain 'B':
    Compound: 11-mer peptide from C-jun-amino-terminal kinase interacting protein 1
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ukhA (A:)
msrskrdnnfysveigdstftvlkryqnlkpigsgaqgivcaaydailernvaikklsrp
fqnqthakrayrelvlmkcvnhkniigllnvftpqksleefqdvyivmelmdanlcqviq
meldhermsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglartagtsf
mmtpyvvtryyrapevilgmgykenvdiwsvgcimgemikggvlfpgtdhidqwnkvieq
lgtpcpefmkklqptvrtyvenrpkyagysfeklfpdvlfpadsehnklkasqardllsk
mlvidaskrisvdealqhpyinvwydpseaeapppkipdkqlderehtieewkeliykev
mdlhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1ukhA (A:)
nfysveigdstftvlkryqnlkpigsgaqgivcaaydailernvaikklsrpfqnqthak
rayrelvlmkcvnhkniigllnvftpqksleefqdvyivmelmdanlcqviqmeldherm
syllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglyyrapevilgmgyken
vdiwsvgcimgemikggvlfpgtdhidqwnkvieqlgtpcpefmkklqptvrtyvenrpk
yagysfeklfpdvlfpnklkasqardllskmlvidaskrisvdealqhpyinvwydpsea
eapppkieewkeliykevmdl

  • Chain 'B':
    No sequence available.