PDB entry 1uk4

View 1uk4 on RCSB PDB site
Description: Crystal structure of SARS Coronavirus Main Proteinase (3CLpro) Complexed With An Inhibitor
Class: hydrolase
Keywords: anti-parallel b-barrel, anti-parallel a-helices, an inhibitor
Deposited on 2003-08-14, released 2003-11-18
The last revision prior to the SCOP 1.75 freeze date was dated 2003-11-18, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.213
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3C-like proteinase
    Species: Human SARS coronavirus
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1uk4a_
  • Chain 'B':
    Compound: 3C-like proteinase
    Species: Human SARS coronavirus
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.75: d1uk4b_
  • Chain 'G':
    Compound: 5-mer peptide of inhibitor
    Species: synthetic, synthetic
  • Chain 'H':
    Compound: 5-mer peptide of inhibitor
    Species: synthetic, synthetic
  • Chain 'K':
    Compound: 5-mer peptide of inhibitor
    Species: synthetic, synthetic
  • Heterogens: ATO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1uk4A (A:)
sgfrkmafpsgkvegcmvqvtcgtttlnglwlddtvycprhvictaedmlnpnyedllir
ksnhsflvqagnvqlrvighsmqncllrlkvdtsnpktpkykfvriqpgqtfsvlacyng
spsgvyqcamrpnhtikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegk
fygpfvdrqtaqaagtdttitlnvlawlyaavingdrwflnrftttlndfnlvamkynye
pltqdhvdilgplsaqtgiavldmcaalkellqngmngrtilgstiledeftpfdvvrqc
sgvtfq

    Sequence, based on observed residues (ATOM records): (download) 
    >1uk4A (A:)
frkmafpsgkvegcmvqvtcgtttlnglwlddtvycprhvictaedmlnpnyedllirks
nhsflvqagnvqlrvighsmqncllrlkvdtsnpktpkykfvriqpgqtfsvlacyngsp
sgvyqcamrpnhtikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegkfy
gpfvdrqtaqaagtdttitlnvlawlyaavingdrwflnrftttlndfnlvamkynyepl
tqdhvdilgplsaqtgiavldmcaalkellqngmngrtilgstiledeftpfdvvrqcsg
v

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1uk4B (B:)
sgfrkmafpsgkvegcmvqvtcgtttlnglwlddtvycprhvictaedmlnpnyedllir
ksnhsflvqagnvqlrvighsmqncllrlkvdtsnpktpkykfvriqpgqtfsvlacyng
spsgvyqcamrpnhtikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegk
fygpfvdrqtaqaagtdttitlnvlawlyaavingdrwflnrftttlndfnlvamkynye
pltqdhvdilgplsaqtgiavldmcaalkellqngmngrtilgstiledeftpfdvvrqc
sgvtfq

    Sequence, based on observed residues (ATOM records): (download) 
    >1uk4B (B:)
sgfrkmafpsgkvegcmvqvtcgtttlnglwlddtvycprhvictaedmlnpnyedllir
ksnhsflvqagnvqlrvighsmqncllrlkvdtsnpktpkykfvriqpgqtfsvlacyng
spsgvyqcamrpnhtikgsflngscgsvgfnidydcvsfcymhhmelptgvhagtdlegk
fygpfvdrqtaqaagtdttitlnvlawlyaavingdrwflnrftttlndfnlvamkynye
pltqdhvdilgplsaqtgiavldmcaalkellqngmngrtilgstiledeftpfdvvrqc
sg

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.

  • Chain 'K':
    No sequence available.